Huffman C, Wagman G, Fudim M, Zolty R, Vittorio T
Department of Internal Medicine, Mount Sinai Hospital, New York, NY 10029, USA.
Transplant Proc. 2010 Nov;42(9):3673-8. doi: 10.1016/j.transproceed.2010.08.034.
End-stage renal disease, cirrhosis, obesity, tachycardia, and extreme stress have all been shown to result in impaired left ventricular function. It is becoming clear, however, that the cardiomyopathies associated with these states are reversible after resolution of the underlying process. In this article, we present the current data demonstrating that renal transplantation, liver transplantation, and bariatric surgery can lead to reversal of uremic, cirrhotic, and obesity cardiomyopathies, respectively. We also discuss the reversibility of tachycardia-induced cardiomyopathy after radiofrequency ablation or pharmacologic therapy for rate or rhythm control and the reversibility of stress-induced cardiomyopathy with supportive care.
终末期肾病、肝硬化、肥胖、心动过速和极度应激均已被证明会导致左心室功能受损。然而,越来越清楚的是,与这些状态相关的心肌病在潜在病因消除后是可逆的。在本文中,我们展示了当前的数据,表明肾移植、肝移植和减肥手术分别可导致尿毒症性、肝硬化性和肥胖性心肌病的逆转。我们还讨论了在进行射频消融或药物治疗以控制心率或心律后,心动过速性心肌病的可逆性,以及支持性治疗下应激性心肌病 的可逆性。