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影响肥胖患者全膝关节置换术后健康相关生活质量的因素。

Factors influencing health-related quality of life after TKA in patients who are obese.

机构信息

Hospital Clinic Barcelona, University of Barcelona, Barcelona, Spain.

出版信息

Clin Orthop Relat Res. 2011 Apr;469(4):1148-53. doi: 10.1007/s11999-010-1671-3. Epub 2010 Nov 23.

Abstract

BACKGROUND

Although the health-related quality of life (HRQL) for patients who are obese seems to improve after TKA, the magnitude of improvement and the associated factors remain controversial. We previously found body mass index was not associated with changes in HRQL after TKA.

QUESTIONS/PURPOSES: The purposes of this secondary analysis were to determine which patient characteristics and surgical factors were associated with worse health status after TKA in patients who are severe or morbidly obese.

METHODS

We assessed 60 patients (53 females; mean age, 70 years) 12 months after surgery. The mean number of comorbidities was 2.5. Mean lower limb anthropometric index scores were: suprapatellar, 1.6; infrapatellar, 2; and suprapatellar/infrapatellar, 1.2. Intraoperative difficulty (IOD) was Grade 0, 40%; Grade 1, 48%; and Grade 2, 12%. Ten patients (17%) had complications. We measured HRQL using the disease-specific WOMAC questionnaire. Patient characteristics (sociodemographic variables, BMI, comorbidity, lower limb anthropometry) and surgical factors (IOD, complications, postoperative medical data) were collected. Associations between WOMAC dimension scores at 12 months and patient characteristics and surgical factors were analyzed using linear regression models.

RESULTS

Factors associated with worse WOMAC dimension scores in patients who were obese included the number of comorbidities, an infrapatellar index percentile less than 75, IOD Grade 2, and the number of complications after discharge.

CONCLUSIONS

For patients with knee osteoarthritis who were severe or morbidly obese, various lower limb anthropometric features, degree of IOD, and postoperative complications negatively influenced postoperative WOMAC scores.

LEVEL OF EVIDENCE

Level II Prognostic Study. See Guidelines for a complete description of levels of evidence.

摘要

背景

尽管肥胖患者的健康相关生活质量(HRQL)在接受 TKA 后似乎有所改善,但改善的幅度和相关因素仍存在争议。我们之前发现体重指数与 TKA 后 HRQL 的变化无关。

问题/目的:本次二次分析的目的是确定哪些患者特征和手术因素与严重或病态肥胖患者接受 TKA 后健康状况恶化有关。

方法

我们在手术后 12 个月评估了 60 名患者(53 名女性;平均年龄 70 岁)。平均合并症数为 2.5。下肢人体测量指数评分分别为:髌上 1.6;髌下 2;髌上/髌下 1.2。术中难度(IOD)为 0 级,40%;1 级,48%;2 级,12%。10 名患者(17%)出现并发症。我们使用特定于疾病的 WOMAC 问卷来测量 HRQL。收集患者特征(社会人口统计学变量、BMI、合并症、下肢人体测量)和手术因素(IOD、并发症、术后医疗数据)。使用线性回归模型分析 WOMAC 维度评分与患者特征和手术因素之间的相关性。

结果

肥胖患者 WOMAC 维度评分较差的相关因素包括合并症数量、髌下指数百分位数小于 75、IOD 等级 2 以及出院后并发症数量。

结论

对于患有膝关节骨关节炎的严重或病态肥胖患者,各种下肢人体测量特征、IOD 程度和术后并发症会对术后 WOMAC 评分产生负面影响。

证据水平

II 级预后研究。有关证据水平的完整描述,请参见指南。

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