Department of Anesthesiology, Hospital USP La Colina, SC de Tenerife, 38006 Tenerife, Spain.
Anesth Analg. 2011 Feb;112(2):477-80. doi: 10.1213/ANE.0b013e318202cd03. Epub 2010 Dec 2.
Selective sensory spinal anesthesia preserves lower limb motor function and thus facilitates postanesthesia care unit (PACU) bypass and reduces ambulation recovery time.
We compared the ambulation time and PACU bypass rate after using 3 low-dose, low-concentration levobupivacaine-fentanyl spinal solutions (5, 4, and 3 mg + 10 μg) in a double-blind study consisting of 90 patients (ASA physical status I and II) scheduled to undergo knee arthroscopy.
The 3-mg dose was halted because of a large number of inadequate blocks (50%). Twenty-three percent and 80% of patients from groups 5 mg and 4 mg, respectively, bypassed the PACU (P = 0001). Ambulation took place after 70 minutes (30-130 minutes) (median [range]) in group 5 mg and 45 minutes (23-120 minutes) in group 4 mg (P = 0006).
Four milligrams levobupivacaine plus 10 μg fentanyl produced adequate surgical anesthesia with the shortest time to ambulation and the highest PACU bypass rate.
选择性感觉性脊髓麻醉保留下肢运动功能，从而便于术后恢复室（PACU）旁路，并减少步行恢复时间。
我们比较了 90 例接受膝关节镜检查的 ASA 体格状况 I 和 II 级患者，在一项双盲研究中使用 3 种低剂量、低浓度左旋布比卡因-芬太尼脊髓溶液（5、4 和 3mg+10μg）后的步行时间和 PACU 旁路率。
由于大量阻滞不完善（50%），停止使用 3mg 剂量。分别有 23%和 80%的 5mg 和 4mg 组患者绕过 PACU（P=0.0001）。5mg 组的步行时间为 70 分钟（30-130 分钟）（中位数[范围]），4mg 组为 45 分钟（23-120 分钟）（P=0.0006）。
4mg 左旋布比卡因加 10μg 芬太尼产生了足够的手术麻醉效果，步行时间最短，PACU 旁路率最高。
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