Ravert Patricia K, Huffaker Crystal
Brigham Young University, Provo, Utah 84602, USA.
J Am Acad Nurse Pract. 2010 Dec;22(12):668-73. doi: 10.1111/j.1745-7599.2010.00564.x. Epub 2010 Nov 5.
To (a) conduct a thorough search of the literature for breast cancer screening studies utilizing mammography, ultrasound, or breast magnetic resonance imaging (MRI), and (b) critically appraise these studies to aid the nurse practitioner in choosing the most appropriate screening tool for their individual patients.
Articles were identified from the following databases: CINAHL, Medline, PubMed, EBSCO, ISI, and Cochrane Library. Reference lists from all articles were reviewed and an authority in breast cancer screening was contacted regarding the reference list.
Breast MRI had a higher sensitivity than mammography and ultrasound in all studies comparing breast MRI. The specificity was lower for breast MRI than for mammography in five out of six studies. The ultrasound had a higher sensitivity than mammography in all five studies examining women with dense breast tissue.
Women who fall into high-risk categories should be screened yearly with breast MRI and mammography. Women with dense breast tissue according to a standardized density score should be screened yearly with ultrasound and mammography. Women in the general population should be screened yearly with mammography.
(a) 全面检索利用乳房X线摄影、超声或乳腺磁共振成像(MRI)进行乳腺癌筛查研究的文献,(b) 严格评估这些研究,以帮助执业护士为其个体患者选择最合适的筛查工具。
文章从以下数据库中识别:护理学与健康领域数据库(CINAHL)、医学在线数据库(Medline)、医学期刊数据库(PubMed)、EBSCO数据库、科学信息研究所(ISI)数据库以及考克兰图书馆。对所有文章的参考文献列表进行了审查,并就参考文献列表联系了一位乳腺癌筛查领域的权威人士。
在所有比较乳腺MRI的研究中,乳腺MRI的敏感性高于乳房X线摄影和超声。在六项研究中的五项中,乳腺MRI的特异性低于乳房X线摄影。在所有五项针对乳腺组织致密女性的研究中,超声的敏感性高于乳房X线摄影。
高危类别女性应每年接受乳腺MRI和乳房X线摄影筛查。根据标准化密度评分显示乳腺组织致密的女性应每年接受超声和乳房X线摄影筛查。一般人群中的女性应每年接受乳房X线摄影筛查。