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[儿童支气管分支缺陷和支气管黏膜憩室病作为肺部慢性炎症过程发展的易感因素]

[Branching defects and mucosal diverticulosis of the bronchi in children as factors predisposing to the development of chronic inflammatory processes in the lungs].

作者信息

Esipova I K, Vladimirtseva A L, Biriukov V V

出版信息

Arkh Patol. 1990;52(2):6-10.

PMID:2112910
Abstract

Clinical and bronchographic data were juxtaposed with the results of selective histological examination of the resected parts of lungs from 3 to 14-year-old children suffering for several years from persistent cough and recurrent pneumonias. The defects of small and mean bronchi branching are found in 66% of cases (out of 50) and in 64% there was diverticulosis of the mucous membrane of large and small bronchi that is followed by pseudopoliposis and the development of deep "pouches". All this is followed by bronchus-associated lymphoid tissue hyperplasia, development of peribronchial pneumonia foci, chronic bronchitis, obturation syndrome.

摘要

对患有数年持续性咳嗽和反复肺炎的3至14岁儿童,将其临床和支气管造影数据与切除肺组织的选择性组织学检查结果进行了对照。在50例病例中,66%发现小支气管和中等支气管分支存在缺陷,64%存在大、小支气管黏膜憩室病,继之出现假息肉形成和深部“袋状”结构的发展。所有这些均伴有支气管相关淋巴组织增生、支气管周围肺炎病灶形成、慢性支气管炎、闭塞综合征。

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