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肯尼亚儿科人群获得性颈部肿块的模式。

Pattern of acquired neck masses in a Kenyan paediatric population.

机构信息

Department of Surgery, University of Nairobi, Kenya.

出版信息

Int J Oral Maxillofac Surg. 2011 Apr;40(4):384-7. doi: 10.1016/j.ijom.2010.10.019. Epub 2010 Dec 3.

Abstract

Acquired paediatric neck masses constitute a diagnostic challenge. Their pattern is important in formulating management protocol. Reports from developing countries including Kenya are scarce. This study describes the causes, location, clinical features and gender distribution of these masses in a Kenyan paediatric population. This prospective cross-sectional study was carried out in a regional Eastern and Central African referral centre in Kenya. Children aged 16 years and below with neck masses, who presented to various clinics and wards in a 5 month period were examined. One hundred and eighty four of 235 masses (78%) were acquired. Inflammatory cases were the most common (64%), followed by malignant neoplasm (32%). The most common inflammatory cases were abscesses, reactive lymphadenopathy and tuberculous adenitis. They mainly involved upper cervical and submandibular lymph nodes and were more prevalent in those aged less than 4 years. Lymphomas were the most common malignant masses (42%). Malignant masses were widespread in location; non-tender, and most frequent in those aged 4-8 years. In conclusion, inflammatory conditions consistent with upper airway infection cause most acquired paediatric neck masses, but malignant neoplasms constitute a significant proportion. Prudent management of infection and early confirmation of diagnosis are recommended.

摘要

获得性儿科颈部肿块构成了诊断挑战。它们的模式对于制定管理方案很重要。包括肯尼亚在内的发展中国家的报告很少。本研究描述了肯尼亚儿科人群中这些肿块的病因、位置、临床特征和性别分布。这项前瞻性的横断面研究在肯尼亚的一个东非和中非区域转诊中心进行。在 5 个月的时间内,对在各个诊所和病房就诊的年龄在 16 岁及以下有颈部肿块的儿童进行了检查。在 235 个肿块中,有 184 个(78%)是获得性的。炎性病例最常见(64%),其次是恶性肿瘤(32%)。最常见的炎性病例是脓肿、反应性淋巴结病和结核性腺炎。它们主要涉及上颈部和颌下淋巴结,在 4 岁以下的儿童中更为常见。淋巴瘤是最常见的恶性肿块(42%)。恶性肿块分布广泛,无触痛,4-8 岁年龄组最为常见。总之,与上呼吸道感染一致的炎症性疾病引起了大多数获得性儿科颈部肿块,但恶性肿瘤构成了相当大的比例。建议谨慎处理感染并尽早确认诊断。

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