Jim Jeffrey, Moon Marc R, Rubin Brian G, Sicard Gregorio A, Sanchez Luis A
Section of Vascular Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Ann Vasc Surg. 2011 Jul;25(5):598-604. doi: 10.1016/j.avsg.2010.10.003. Epub 2010 Dec 4.
Traditional open repair of distal arch aortic aneurysms requires a two-stage procedure associated with significant morbidity and mortality. The introduction of thoracic endovascular aneurysm repair has created a less invasive option to complete the second stage of the repair after proximal elephant trunk creation. The present study reports a series of patients treated with a combined open proximal and endovascular distal repair of distal arch aortic aneurysms.
A retrospective review was undertaken at a university medical center. All patients treated with the hybrid approach were identified. The patients were evaluated for demographics, preoperative imaging, technical success, postoperative complications, length of hospital stay, need for secondary intervention, and overall survival.
A total of 10 patients (3 men, mean age: 67.5 years) were identified during a 4-year period between August 2005 and July 2009. All patients were treated electively and the mean maximum aneurysm diameter was 70.8 mm. Of the 10 patients, four had undergone previous thoracotomy (three aortic repair, one pulmonary resection for malignancy) and all were deemed at prohibitive risk for open second-stage surgery. The first three patients had staged reconstruction with delayed endovascular intervention through retrograde arterial access. The more recent seven patients underwent single-stage repair with endograft delivery through an antegrade ascending aortic access. Technical success was achieved in all cases. No perioperative paraplegias or strokes were reported. One patient had successful endovascular treatment of a type IB endoleak at 38 months. Another had an enlarging thoracoabdominal aneurysm resulting in a type IB endoleak which was detected at 43 months. There was one death within 30 days after the procedure. The remaining nine patients are all alive, with a mean survival of 35.1 months (range: 8-53) after surgery.
The hybrid approach to treatment of distal arch aortic aneurysms is safe and serves as a viable alternative to conventional open repair. Less technically challenging, avoidance of a second surgery as well as elimination of the possibility of becoming lost to follow-up, or interval mortality have led us to consider a single-stage repair using an antegrade approach as the preferred option.
传统的远端主动脉弓部动脉瘤开放修复术需要分两阶段进行,且并发症和死亡率较高。胸主动脉腔内修复术的出现为在近端象鼻支架置入术后完成修复的第二阶段提供了一种侵入性较小的选择。本研究报告了一系列采用近端开放和远端腔内联合修复远端主动脉弓部动脉瘤的患者。
在一所大学医学中心进行了一项回顾性研究。确定所有采用杂交手术方法治疗的患者。对患者进行人口统计学、术前影像学、技术成功率、术后并发症、住院时间、二次干预需求及总生存率评估。
在2005年8月至2009年7月的4年期间共确定了10例患者(3例男性,平均年龄67.5岁)。所有患者均为择期手术,动脉瘤平均最大直径为70.8mm。10例患者中,4例曾接受过开胸手术(3例主动脉修复,1例因恶性肿瘤行肺切除术),均被认为进行开放二期手术的风险极高。前三例患者采用分期重建,通过逆行动脉通路进行延迟腔内干预。最近的7例患者采用单阶段修复,通过顺行升主动脉通路输送腔内移植物。所有病例均取得技术成功。未报告围手术期截瘫或中风。1例患者在38个月时成功进行了IB型内漏的腔内治疗。另1例患者出现胸腹主动脉瘤扩大,导致43个月时发现IB型内漏。术后30天内有1例死亡。其余9例患者均存活,术后平均生存35.1个月(范围:8 - 53个月)。
杂交手术治疗远端主动脉弓部动脉瘤是安全的,是传统开放修复术的可行替代方案。技术难度较低,避免了二次手术以及随访失访或间期死亡的可能性,使我们认为采用顺行方法的单阶段修复是首选方案。