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实验动物管理与使用委员会对鸣禽及其在神经生物学研究中的应用的看法。

An IACUC perspective on songbirds and their use in neurobiological research.

作者信息

Schmidt Marc F

机构信息

Department of Biology, 312 Leidy Laboratories, University of Pennsylvania, 433 South University Avenue, Philadelphia, PA 19104-6018, USA.

出版信息

ILAR J. 2010;51(4):424-30. doi: 10.1093/ilar.51.4.424.

Abstract

Laboratory research using songbirds as a model system for investigating basic questions of neurobiological function has expanded rapidly and recently, with approximately 120 laboratories working with songbirds worldwide. In the United States alone, of the approximately 80 such laboratories nearly a third have been established in the past 10 years. Yet many animal facilities are not outfitted to manage these animals, and as a consequence laboratories often use alternative housing arrangements established by institutional animal care and use committees (IACUCs). These committees invariably differ in their expertise level with birds and thus guidelines also vary considerably from one institution to another. In this article I address a number of factors to consider for effective oversight of research involving songbirds.

摘要

利用鸣禽作为模型系统来研究神经生物学功能基本问题的实验室研究近来迅速发展,目前全球约有120个实验室在开展与鸣禽相关的研究。仅在美国,在约80个这样的实验室中,近三分之一是在过去10年里建立的。然而,许多动物设施并未配备管理这些动物的条件,因此实验室常常采用机构动物护理和使用委员会(IACUCs)制定的替代饲养安排。这些委员会在鸟类专业知识水平上各不相同,所以各机构的指导方针也差异很大。在本文中,我阐述了对涉及鸣禽的研究进行有效监督时需要考虑的一些因素。

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