Am J Gastroenterol. 2010 Dec;105(12):2607-9. doi: 10.1038/ajg.2010.347.
Since Kappis first performed percutaneous neurolysis in 1914, investigators have employed innumerable technical variations in an effort to enhance the efficacy. Similar efforts have been underway by endosonographers since Wiersema performed the first endoscopic ultrasound (EUS)-guided celiac plexus neurolysis in 1996. Although such efforts are important, the availability of multiple procedural options is indicative of the controversy and lack of meaningful progress. If one particular method was clearly superior, the other techniques would have become obsolete. Sakamoto et al. present a new method of EUS-guided neurolysis in an attempt to improve the outcomes. Although their data are promising, we eagerly await rigorously designed studies that may validate their findings.
自 1914 年 Kappis 首次进行经皮神经松解术以来，研究人员采用了无数种技术变化，试图提高疗效。自 1996 年 Wiersema 进行首例内镜超声（EUS）引导腹腔神经丛神经松解术以来，内镜超声医师也一直在进行类似的努力。尽管这些努力很重要，但多种手术选择的出现表明存在争议和缺乏有意义的进展。如果一种特定的方法明显更优越，那么其他技术就会被淘汰。Sakamoto 等人提出了一种新的 EUS 引导神经松解方法，试图改善治疗效果。尽管他们的数据很有希望，但我们急切地等待着精心设计的研究，这些研究可能会验证他们的发现。
