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[影响缺血性中风溶栓治疗时间延迟的因素]

[Factors that affect time delays to fibrinolytic treatment in ischaemic stroke].

作者信息

Palomino-García Alfredo, Moniche-Álvarez Francisco, de la Torre-Laviana Francisco J, Cayuela-Domínguez Aurelio, Vigil Eduardo, Jiménez-Hernández M Dolores

机构信息

Servicio de Neurología, Hospital Universitario Virgen del Rocío, Sevilla, España.

出版信息

Rev Neurol. 2010 Dec 16;51(12):714-20.

Abstract

INTRODUCTION

Extending the thrombolytic therapy window in ischaemic stroke to 4.5 hours has proved to be useful and safe, but a prompt response remains a decisive factor.

AIM

To analyse the factors that delay treatment.

PATIENTS AND METHODS

After activating the Stroke Code procedure, the consecutive cases of stroke attended in the emergency department throughout the year 2006 were recorded; data included their clinical and epidemiological features, origin, means of transport and delay times in the process.

RESULTS

Of the total number of patients with ischaemic stroke, 10.1% finished the emergency study with a median of 1 hour to decide to carry out treatment within 3 hours, and 13.1% of them between 3 and 4.5 hours, with a median of 2 hours and 6 minutes. For the analysis of all the variables, 498 patients were selected; 39% were admitted to hospital within the first 3 hours and 11.2% between 3 and 4.5 hours of the onset of symptoms. The use of the emergency telephone system, transport by mobile ICU or ambulance and an impaired level of consciousness, sight or, to a lesser extent, language or speech were related to shorter delay times.

CONCLUSIONS

The factors that depended on the actual patient, in general, did not shorten the delay time. Clinical severity, the presence of informants and activating the emergency system shortened intervention times.

摘要

引言

将缺血性中风的溶栓治疗窗口延长至4.5小时已被证明是有用且安全的,但迅速反应仍然是一个决定性因素。

目的

分析延误治疗的因素。

患者与方法

启动中风代码程序后,记录了2006年全年急诊科接诊的连续中风病例;数据包括其临床和流行病学特征、来源、交通方式以及过程中的延误时间。

结果

在缺血性中风患者总数中,10.1%在1小时中位数内完成急诊检查,以决定在3小时内进行治疗,其中13.1%在3至4.5小时内完成,中位数为2小时6分钟。为分析所有变量,选取了498例患者;39%在症状发作后的前3小时内入院,11.2%在症状发作后3至4.5小时内入院。使用紧急电话系统、由移动重症监护病房或救护车运送以及意识水平、视力受损,在较小程度上语言或言语受损与较短的延误时间相关。

结论

一般来说,取决于实际患者的因素并未缩短延误时间。临床严重程度、有告知者以及启动应急系统缩短了干预时间。

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