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半旋转动脉干加动脉调转术治疗大动脉转位合并室间隔缺损和流出道梗阻。

Half rotation of the truncus arteriosus plus arterial switch for transposition of the great arteries with ventricular septal defect and pulmonary outflow tract obstruction.

机构信息

Department of Cardiovascular Surgery, Northern Hospital, Shenhe District, Shenyang City, Liaoning Province, PR China.

出版信息

Eur J Cardiothorac Surg. 2011 Sep;40(3):579-83. doi: 10.1016/j.ejcts.2010.10.041. Epub 2010 Dec 15.

Abstract

OBJECTIVE

The goal of our study was to report our experience of using half rotation of the truncus arteriosus plus arterial switch, as a modification of the Nikaidoh procedure, for anatomic repair of transposition of the great arteries (TGA) with ventricular septal defect (VSD) and pulmonary outflow tract obstruction (pulmonary stenosis (PS)).

METHODS

From December 2006 to December 2009, 11 patients (six male, five female) underwent half rotation of the truncus arteriosus plus arterial switch for repair of TGA, VSD, and PS or double-outlet right ventricle (DORV) at our heart center.

RESULTS

There was no operative death. All patients had relief of left ventricular outflow tract obstruction (LVOTO) as determined by direct pressure measurements intraoperatively. Echocardiography was performed for all patients intraoperatively and before discharge. Two patients had mild aortic regurgitation and two patients had mild pulmonary regurgitation. For a median follow-up of 15 months (range 6-42 months), all patients were alive. Echocardiography was performed at 3, 6, 12, 24 and 36 postoperative months. All patients have normal ventricular function. No evidence of LVOTO was founded in all patients. Two patients had mild aortic regurgitation and three patients had mild to medium pulmonary regurgitation.

CONCLUSIONS

Half rotation of the truncus arteriosus plus arterial switch, as a modification of the Nikaidoh procedure, is a good alternative treatment for complete anatomic repair for TGA, VSD, and PS or DORV with malposition of great arteries and PS. The technique might allow to reconstruct biventricular outflow tract, preserve competence and growth potential of the pulmonary root with valves and decrease the probability of reoperation. Its long-term benefits need to be evaluated with a large number of patients and longer follow-up.

摘要

目的

我们研究的目的是报告我们使用半旋转动脉干加动脉调转术(Truncus arteriosus plus arterial switch,TAS)的经验,作为 Nikaidoh 手术的改良,用于解剖修复大动脉转位(Transposition of the great arteries,TGA)合并室间隔缺损(Ventricular septal defect,VSD)和流出道梗阻(Pulmonary stenosis,PS)。

方法

自 2006 年 12 月至 2009 年 12 月,我们心脏中心对 11 例(男 6 例,女 5 例)TGA、VSD 和 PS 或双出口右心室(Double-outlet right ventricle,DORV)患者施行半旋转动脉干加动脉调转术进行解剖修复。

结果

无手术死亡。所有患者术中直接测量压力均解除左心室流出道梗阻(Left ventricular outflow tract obstruction,LVOTO)。所有患者术中及出院前均行超声心动图检查。2 例患者主动脉瓣轻度反流,2 例患者肺动脉瓣轻度反流。中位随访 15 个月(6-42 个月),所有患者均存活。术后 3、6、12、24 和 36 个月进行超声心动图检查。所有患者心室功能正常。所有患者均未发现 LVOTO。2 例患者主动脉瓣轻度反流,3 例患者主动脉瓣轻度至中度反流。

结论

半旋转动脉干加动脉调转术(Truncus arteriosus plus arterial switch,TAS)作为 Nikaidoh 手术的改良,是 TGA、VSD、PS 或 DORV 合并大动脉位置异常和 PS 的完全解剖修复的良好替代治疗方法。该技术可能允许重建双心室流出道,保留带瓣肺动脉干的功能和生长潜力,降低再次手术的概率。其长期效果需要更多患者和更长时间的随访来评估。

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