肠炎沙门氏菌O59和大肠杆菌O15的O-多糖结构
Structures of the O-polysaccharides of Salmonella enterica O59 and Escherichia coli O15.
作者信息
Perepelov Andrei V, Liu Bin, Senchenkova Sof'ya N, Shashkov Alexander S, Guo Dan, Feng Lu, Knirel Yuriy A, Wang Lei
机构信息
N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991 Moscow, Russian Federation.
出版信息
Carbohydr Res. 2011 Feb 1;346(2):381-3. doi: 10.1016/j.carres.2010.11.017. Epub 2010 Nov 20.
The O-polysaccharide of Salmonella enterica O59 was studied using sugar analysis and 2D (1)H and (13)C NMR spectroscopy, and the following structure of the tetrasaccharide repeating unit was established: →2)-β-d-Galp-(1→3)-α-d-GlcpNAc-(1→4)-α-l-Rhap-(1→3)-β-d-GlcpNAc-(1→ Accordingly, the O-antigen gene cluster of S. enterica O59 includes all genes necessary for the synthesis of this O-polysaccharide. Earlier, another structure has been reported for the O-polysaccharide of Salmonella arizonae (S. enterica IIIb) O59, which later was found to be identical to that of Citrobacter (Citrobacter braakii) O35 and, in this work, also to the O-polysaccharide of Escherichia coli O15.
利用糖分析以及二维氢谱和碳谱核磁共振波谱对肠炎沙门氏菌O59的O-多糖进行了研究，确定了四糖重复单元的如下结构：→2)-β-D-吡喃半乳糖-(1→3)-α-D-吡喃葡萄糖胺-(1→4)-α-L-鼠李糖-(1→3)-β-D-吡喃葡萄糖胺-(1→ 因此，肠炎沙门氏菌O59的O抗原基因簇包含合成该O-多糖所需的所有基因。此前，已报道了亚利桑那沙门氏菌（肠炎沙门氏菌IIIb）O59的O-多糖的另一种结构，后来发现其与布氏柠檬酸杆菌O35的结构相同，并且在本研究中还与大肠杆菌O15的O-多糖相同。
Zotero 插件