病毒性根除后伴有门静脉血栓形成的肝细胞癌，经5-氟尿嘧啶和干扰素治疗后消失。
Hepatocellular carcinoma, with portal thrombus after viral eradication, disappeared by 5-fluorouracil and interferon.
作者信息
Miura Tomofumi, Suzuki Nobuaki, Nakamura Junichiro, Yamada Satoshi, Miura Tsutomu, Yanagi Masahiko, Usuda Hiroyuki, Emura Iwao, Takahashi Toru
机构信息
Tomofumi Miura, Nobuaki Suzuki, Junichiro Nakamura, Satoshi Yamada, Tsutomu Miura, Masahiko Yanagi, Toru Takahashi, Division of Gastroenterology and Hepatology, Nagaoka Red Cross Hospital, 2-297-1, Senshu, Nagaoka, Niigata 940-2085, Japan.
出版信息
World J Hepatol. 2010 Nov 27;2(11):416-8. doi: 10.4254/wjh.v2.i11.416.
Hepatocarcinogenesis after a sustained virological response (SVR) in type C chronic hepatitis and cirrhosis is an important issue in endemic areas; hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT) therapy is especially very hard. We herein report a first case in which combination therapy with interferon-α and continuous intra-arterial infusion of 5-fluorouracil (designated as FAIT) provided a complete response in HCC with PVTT after SVR. Therefore, we think that FAIT is a good option to treat HCC with or without PVTT, even after SVR.
在丙型慢性肝炎和肝硬化患者实现持续病毒学应答（SVR）后发生肝癌是流行地区的一个重要问题；伴有门静脉癌栓（PVTT）的肝细胞癌（HCC）治疗尤其困难。我们在此报告首例在SVR后采用α干扰素联合5-氟尿嘧啶持续动脉内输注（称为FAIT）治疗伴有PVTT的HCC获得完全缓解的病例。因此，我们认为FAIT是治疗伴有或不伴有PVTT的HCC的一个良好选择，即使是在SVR之后。
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