McGrady Michael G, Ellwood Roger P, Pretty Iain A
School of Dentistry, The University of Manchester, Higher Cambridge Street, Manchester, UK.
Dent Update. 2010 Nov;37(9):595-8, 601-2. doi: 10.12968/denu.2010.37.9.595.
Fluoride has been used in dentistry for over 100 years for the purpose of preventing dental caries. During this time there has been great debate over the mode of action, the optimum method of delivery, and the potential risks associated with its use. This, the first of three papers, will provide a summary of the history of the use of fluoride, the mode of action, benefits and different methods of delivery. It will also discuss the potential risk of dental fluorosis.
This article aims to provide a background for general practitioners for the appropriate use of fluorides in dentistry, enable them to understand the wider significance of fluoride in dentistry and to be able to answer non-clinical questions raised by patients.
氟化物在牙科领域已使用超过100年，用于预防龋齿。在此期间，关于其作用方式、最佳给药方法以及使用相关潜在风险存在诸多争论。这是三篇论文中的第一篇，将概述氟化物的使用历史、作用方式、益处及不同给药方法。还将讨论氟斑牙的潜在风险。
本文旨在为全科医生提供在牙科领域合理使用氟化物的背景知识，使他们理解氟化物在牙科领域更广泛的意义，并能够回答患者提出的非临床问题。
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