Lassen C L, Kleinjung T, Strutz J, Graf B M, Wiese C H R
Klinik für Anästhesiologie, Universitätsklinikum Regensburg, Franz-Josef-Strauss-Allee-11, 93053 Regensburg, Deutschland.
Schmerz. 2011 Feb;25(1):89-92. doi: 10.1007/s00482-010-1007-y.
Glossopharyngeal neuralgia is a rare condition and the origin is mostly idiopathic. Causes of symptomatic glossopharyngeal neuralgia can be tumors, infarction or trauma. We report the case of a 28-year-old patient who developed glossopharyngeal neuralgia after resection of a glossopharyngeal schwannoma, which is an extremely rare tumor. Treatment consisted of orally administered pregabalin and a series of injections of buprenorphine in the superior cervical ganglion (ganglionic local opioid application/analgesia, GLOA) which led to a substantial decrease in the frequency of pain attacks. This improvement was maintained at 1-year follow-up. This is the first report of development of glossopharyngeal neuralgia after resection of a glossopharyngeal schwannoma.
舌咽神经痛是一种罕见疾病,其病因大多为特发性。症状性舌咽神经痛的病因可能是肿瘤、梗死或外伤。我们报告一例28岁患者,在切除舌咽神经鞘瘤后发生舌咽神经痛,舌咽神经鞘瘤是一种极其罕见的肿瘤。治疗方法包括口服普瑞巴林以及一系列在颈上神经节注射丁丙诺啡(神经节局部阿片类药物应用/镇痛,GLOA),这使疼痛发作频率大幅降低。这种改善在1年随访中得以维持。这是首例关于舌咽神经鞘瘤切除术后发生舌咽神经痛的报告。