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德斯美氏膜内皮角膜移植自动化(DMAEK):视力结果和视觉质量。

Descemet's membrane automated endothelial keratoplasty (DMAEK): visual outcomes and visual quality.

机构信息

Price Vision Group, Indianapolis, Indiana, USA.

出版信息

Br J Ophthalmol. 2011 Jul;95(7):951-4. doi: 10.1136/bjo.2010.191494. Epub 2010 Dec 22.

Abstract

BACKGROUND/AIMS: To determine whether the stromal rim that carries the bare endothelial graft in Descemet's membrane automated endothelial keratoplasty (DMAEK) has any effect on final visual outcome or visual quality.

METHODS

Twenty-four DMAEK eyes and 22 Descemet's membrane endothelial keratoplasty (DMEK) eyes (with no stromal rim) were evaluated for corrected distance acuity, full-field Humphrey visual field (VF) 120-2 and pupil size. The inner and outer diameter of the DMAEK stromal ring was measured from slit lamp photos. Patients completed a questionnaire rating postoperative symptoms and visual complaints. Exclusion criteria were pre-existing glaucoma, retinal pathology or inability to return for postoperative examinations.

RESULTS

Median Snellen acuities were comparable between DMAEK and DMEK groups: 20/25 and 20/20-3, respectively. The mean central opening of the DMAEK stromal ring was 5.6 × 5.5 (range 3.8-6.9) mm. The incidence of VF defects, visual complaints of glare, halos, light sensitivity and night driving difficulties was comparable between groups (all p > 0.1). A larger scotopic pupil size (< 5.5 mm) was not associated with increased incidence of VF defects in either group (p = 0.3).

CONCLUSIONS

Surprisingly, compared with uniformly thin DMEK grafts, DMAEK grafts with a stromal rim had no increase in VF defects or visual complaints.

摘要

背景/目的:确定在 Descemet 膜自动内皮角膜移植术(DMAEK)中携带裸露内皮移植物的基质边缘是否对最终视力结果或视觉质量有任何影响。

方法

评估了 24 只 DMAEK 眼和 22 只 Descemet 膜内皮角膜移植术(DMEK)眼(无基质边缘)的矫正远视力、全视野 Humphrey 视野 120-2 和瞳孔大小。从裂隙灯照片测量 DMAEK 基质环的内直径和外直径。患者完成了一份问卷,评估术后症状和视觉抱怨。排除标准为先前存在青光眼、视网膜病变或无法返回进行术后检查。

结果

DMAEK 和 DMEK 组的中位数 Snellen 视力相当:分别为 20/25 和 20/20-3。DMAEK 基质环的平均中央开口为 5.6×5.5(范围 3.8-6.9)mm。两组的视野缺损发生率、眩光、晕影、光敏感和夜间驾驶困难的视觉抱怨相似(均 p>0.1)。两组中暗瞳孔大小较小(<5.5mm)均与视野缺损发生率增加无关(p=0.3)。

结论

令人惊讶的是,与均匀薄的 DMEK 移植物相比,带有基质边缘的 DMAEK 移植物并未增加视野缺损或视觉抱怨。

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