Department of Epidemiology and Biostatistics, Drexel University School of Public Health, Philadelphia, PA, USA.
Am J Cardiol. 2011 Mar 1;107(5):655-61. doi: 10.1016/j.amjcard.2010.10.040. Epub 2010 Dec 22.
In the absence of a previous global comparison, we examined the variability in the prevalence of angina across 52 countries and its association with body weight and the poverty index using data from the World Health Organization-World Health Survey. The participants with angina were defined as those who had positive results using a Rose angina questionnaire and/or self-report of a physician diagnosis of angina. The body mass index (BMI) was determined as the weight in kilograms divided by the square of the height in meters. The poverty index (a standard score of socioeconomic status for a given country) was extracted from the United Nations' statistics. The associations of angina with the BMI and poverty index were analyzed cross-sectionally using univariate and multivariate analyses. The results showed that the total participants (n = 210,787) had an average age of 40.64 years. The prevalence of angina ranged from 2.44% in Tunisia to 23.89% in Chad. Those participants with a BMI of <18.5 kg/m(2) (underweight), 25 to 29 kg/m(2) (overweight), or BMI ≥ 30 kg/m(2) (obese) had a significantly greater risk of having angina compared to those with a normal BMI (≥ 18.5 but <25 k/m(2)). The odds ratios of overweight and obese for angina remained significant in the multilevel models, in which the influence of the country-level poverty status was considered. A tendency was seen for underweight status and a poverty index >14.65% to be associated with the risk of having angina, although these associations were not statistically significant in the multilevel models. In conclusion, significant variations were found in the anginal rates across 52 countries worldwide. An increased BMI was significantly associated with the odds of having angina.
在缺乏全球既往比较的情况下,我们利用世界卫生组织-世界卫生调查的数据,研究了 52 个国家心绞痛的流行率差异及其与体重和贫困指数的关系。心绞痛患者的定义为使用罗斯心绞痛问卷阳性结果和/或医生诊断心绞痛的自我报告的患者。体重指数(BMI)定义为体重(千克)除以身高(米)的平方。贫困指数(给定国家的社会经济地位标准分数)从联合国统计数据中提取。使用单变量和多变量分析方法对心绞痛与 BMI 和贫困指数的关系进行了横断面分析。结果显示,共有 210787 名参与者,平均年龄为 40.64 岁。心绞痛的患病率从突尼斯的 2.44%到乍得的 23.89%不等。与 BMI 正常(≥18.5 但<25kg/m(2))的参与者相比,BMI<18.5kg/m(2)(消瘦)、25-29kg/m(2)(超重)或 BMI≥30kg/m(2)(肥胖)的参与者患心绞痛的风险显著增加。在考虑国家贫困状况影响的多层次模型中,超重和肥胖的心绞痛比值比仍然显著。消瘦和贫困指数>14.65%与患心绞痛的风险呈正相关趋势,但在多层次模型中这些相关性没有统计学意义。总之,我们发现全球 52 个国家的心绞痛发生率存在显著差异。BMI 的增加与心绞痛的发生几率显著相关。