Yokomizo Yumiko, Goubara Ayako, Tanaka Katsuyuki, Yokoyama Osamu
The Department of Urology, Kanagawa Rehabilitation Hospital, Japan.
Hinyokika Kiyo. 2010 Nov;56(11):659-61.
The patient was a 72-year-old man with C4 incomplete tetraplegia incurred in a traffic accident in March, 2008. He managed his bladder with an indwelling Foley catheter. In August, 2009, the catheter obstruction induced autonomic dysreflexia (AD). Although distention of bladder disappeared immediately, cerebeller hemorrhage occurred due to AD. After an operation the patient was alive but left with disturbance of consciousness. AD is one of the most important complications of high-level spinal cord injury. The pathophysiology of AD is the disconnection of the spinal sympathetic centers from spuraspinal control, leading to unopposed, sustained sympathetic outflow below the spinal lesion. Clinically, it is characterized by an acute increase in blood pressure, headache, sweating, and facial flushing and is often triggered by nonspecific stimuli below the level of the spinal cord lesion. The main triggering factors are bladder overdistension and bowel distension. Most events subside after prompt recognition and removal of the triggering factors, but, it is a life threatening emergency that may lead to apoplexy. This life-threatening complication should be kept in mind in the patients with spinal cord injury.
该患者为一名72岁男性,2008年3月因交通事故导致C4不完全性四肢瘫痪。他通过留置Foley导尿管来管理膀胱。2009年8月,导尿管堵塞引发了自主神经反射异常(AD)。尽管膀胱扩张立即消失,但由于AD导致了小脑出血。手术后患者存活,但遗留意识障碍。AD是高位脊髓损伤最重要的并发症之一。AD的病理生理学是脊髓交感神经中枢与脊髓以上控制的分离,导致脊髓损伤平面以下出现无对抗的、持续的交感神经输出。临床上,其特征为血压急性升高、头痛、出汗和面部潮红,常由脊髓损伤平面以下的非特异性刺激引发。主要触发因素是膀胱过度扩张和肠道扩张。大多数事件在及时识别并去除触发因素后消退,但这是一种可能导致中风的危及生命的紧急情况。脊髓损伤患者应牢记这种危及生命的并发症。