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[无肺部表现的医源性静脉性脑空气栓塞:一种逆行机制?]

[Iatrogenic venous cerebral air embolism without pulmonary manifestation: A retrograde mechanism?].

作者信息

Raposo N, Faiz F, Albucher J-F, Dugert E, Bonneville F, Meliani P, Chollet F

机构信息

Service de neurologie vasculaire, hôpital Purpan, pavillon Riser, CHU de Toulouse, 31059 Toulouse cedex 3, France.

出版信息

Rev Neurol (Paris). 2011 Aug-Sep;167(8-9):615-8. doi: 10.1016/j.neurol.2010.10.004. Epub 2010 Dec 28.

Abstract

INTRODUCTION

Air embolism is a rare complication of various invasive medical procedures. Venous cerebral air embolism is usually the consequence of paradoxical embolism. We report a case of isolated cerebral air embolism resulting from a non-paradoxical mechanism.

CASE REPORT

A few minutes after his central venous catheter had been accidentally disconnected, a 63-year-old man developed left-sided rhythmic jerking movements followed by left hemiplegia. There were no associated cardiologic or pulmonary signs. Brain CT showed air bubbles in the right frontal cortical sulci. The brain MRI DWI and FLAIR sequences showed a high intensity right frontal cortical lesion without reduction in ADC. Transesophageal echocardiogram did not find a patent foramen ovale.

CONCLUSIONS

In this case of venous cerebral air embolism, the lack of any cardiopulmonary manifestation, the lack of a patent foramen ovale and the neuroradiological findings are not in favor of the hypothesis of paradoxical embolism. The hypothesis of retrograde venous cerebral air embolism is discussed.

摘要

引言

空气栓塞是各种侵入性医疗程序中罕见的并发症。静脉性脑空气栓塞通常是反常栓塞的结果。我们报告一例由非反常机制导致的孤立性脑空气栓塞病例。

病例报告

一名63岁男性的中心静脉导管意外断开几分钟后,出现左侧节律性抽搐运动,随后出现左侧偏瘫。无相关心脏或肺部体征。脑部CT显示右侧额叶皮质沟内有气泡。脑部MRI的DWI和FLAIR序列显示右侧额叶皮质有高强度病变,表观扩散系数(ADC)未降低。经食管超声心动图未发现卵圆孔未闭。

结论

在该例静脉性脑空气栓塞中,缺乏任何心肺表现、卵圆孔未闭以及神经放射学检查结果均不支持反常栓塞的假说。文中讨论了逆行性静脉性脑空气栓塞的假说。

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