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身体活动改善肠易激综合征症状:一项随机对照试验。

Physical activity improves symptoms in irritable bowel syndrome: a randomized controlled trial.

机构信息

Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

出版信息

Am J Gastroenterol. 2011 May;106(5):915-22. doi: 10.1038/ajg.2010.480. Epub 2011 Jan 4.

Abstract

OBJECTIVES

Physical activity has been shown to be effective in the treatment of conditions, such as fibromyalgia and depression. Although these conditions are associated with irritable bowel syndrome (IBS), no study has assessed the effect of physical activity on gastrointestinal (GI) symptoms in IBS. The aim was to study the effect of physical activity on symptoms in IBS.

METHODS

We randomized 102 patients to a physical activity group and a control group. Patients of the physical activity group were instructed by a physiotherapist to increase their physical activity, and those of the control group were instructed to maintain their lifestyle. The primary end point was to assess the change in the IBS Severity Scoring System (IBS-SSS).

RESULTS

A total of 38 (73.7% women, median age 38.5 (19-65) years) patients in the control group and 37 (75.7% women, median age 36 (18-65) years) patients in the physical activity group completed the study. There was a significant difference in the improvement in the IBS-SSS score between the physical activity group and the control group (-51 (-130 and 49) vs. -5 (-101 and 118), P=0.003). The proportion of patients with increased IBS symptom severity during the study was significantly larger in the control group than in the physical activity group.

CONCLUSIONS

Increased physical activity improves GI symptoms in IBS. Physically active patients with IBS will face less symptom deterioration compared with physically inactive patients. Physical activity should be used as a primary treatment modality in IBS.

摘要

目的

运动已被证明对纤维肌痛和抑郁等疾病的治疗有效。尽管这些疾病与肠易激综合征(IBS)有关,但尚无研究评估运动对 IBS 患者胃肠道(GI)症状的影响。本研究旨在探讨运动对 IBS 症状的影响。

方法

我们将 102 名患者随机分为运动组和对照组。运动组的患者由物理治疗师指导增加身体活动,对照组的患者则保持其生活方式。主要终点是评估 IBS 严重程度评分系统(IBS-SSS)的变化。

结果

对照组有 38 名(73.7%女性,中位年龄 38.5(19-65)岁)和运动组有 37 名(75.7%女性,中位年龄 36(18-65)岁)患者完成了研究。运动组与对照组之间 IBS-SSS 评分的改善有显著差异(-51(-130 至 49)与-5(-101 至 118),P=0.003)。在研究期间,IBS 症状严重程度增加的患者比例在对照组明显高于运动组。

结论

增加身体活动可改善 IBS 的 GI 症状。与不活跃的患者相比,IBS 患者中积极运动的患者将面临较少的症状恶化。身体活动应作为 IBS 的主要治疗方式。

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