NEERAJ SINGH GILL, M.D., Senior Resident, National Institute of Mental Health and Neuro Sciences, Bangalore - 560029.
Indian J Psychiatry. 2002 Jan;44(1):29-33.
During electroconvulsive therapy (ECT), occurrence of seizure must be confirmed. Cuff method, although simple and reliable, can sometimes miss an adequate EEG seizure. Predictable cardiovascular response occurs during ECT seizure. We examined if this can be an additional guide to detect cerebral seizure. In 164 modified ECT sessions, EEG and cuff methods were used for seizure monitoring. Heart rate (HR in beats per minute) and blood pressure (BP in mm of Hg) were recorded before (baseline) and 20 seconds after the stimulus (ictal). The rate pressure product (RPP=HR x systolic BP) was computed. The ECT sessions consisted of three groups, viz., adequate EEG and motor seizure (n=126), adequate EEG but not motor seizure (n=21) and neither EEG nor motor seizure adequate (n=17). Significant elevation of RPP occurred from baseline to 'ictal' recording and this was different between the three groups. Ictal RPP did not differ between groups with or without adequate motor seizure if EEG seizure was adequate. The group with no adequate EEG or motor seizure had the least 'ictal' RPP. Findings suggest that RPP response can be an additional clinical measure to detect seizures during ECT.
在电痉挛治疗(ECT)期间,必须确认是否发生了抽搐。袖带法虽然简单可靠,但有时可能会错过充分的脑电图抽搐。ECT 抽搐期间会出现可预测的心血管反应。我们研究了这是否可以作为另一种检测脑抽搐的方法。在 164 次改良 ECT 治疗中,使用脑电图和袖带法监测抽搐。在刺激前(基础)和刺激后 20 秒(抽搐期)记录心率(每分钟心跳数)和血压(mmHg)。计算心率与收缩压的乘积(RPP)。ECT 治疗分为三组:脑电图和运动性抽搐充分(n=126)、脑电图充分但无运动性抽搐(n=21)和脑电图和运动性抽搐均不充分(n=17)。与基础值相比,抽搐期的 RPP 显著升高,且三组之间存在差异。如果脑电图抽搐充分,则具有充分运动性抽搐和无充分运动性抽搐的两组之间的抽搐期 RPP 无差异。如果脑电图或运动性抽搐均不充分,则组中抽搐期的 RPP 最低。研究结果表明,RPP 反应可以作为一种额外的临床措施,以检测 ECT 期间的抽搐。