Golshani Kiarash, Ferrell Andrew, Zomorodi Ali, Smith Tony P, Britz Gavin W
Department of Radiology, Division of Vascular and Interventional Radiology, Duke University Medical Center, Durham North Carolina, USA.
Surg Neurol Int. 2010 Dec 22;1:88. doi: 10.4103/2152-7806.74147.
Technical advancements have significantly improved surgical and endovascular treatment of cerebral aneurysms. In this paper, we review the literature with regard to treatment of one of the most common intra-cranial aneurysms encountered by neurosurgeons and interventional radiologists.
Anterior clinoidectomy, temporary clipping, adenosine-induced cardiac arrest, and intraoperative angiography are useful adjuncts during surgical clipping of these aneurysms. Coil embolization is also an effective treatment alternative particularly in the elderly population. However, coiled posterior communicating artery aneurysms have a particularly high risk of recurrence and must be followed closely. Posterior communicating artery aneurysms with an elongated fundus, true posterior communicating artery aneurysms, and aneurysms associated with a fetal posterior communicating artery may have better outcome with surgical clipping in terms of completeness of occlusion and preservation of the posterior communicating artery. However, as endovascular technology improves, endovascular treatment of posterior communicating artery aneurysms may become equivalent or preferable in the near future. One in five patients with a posterior communicating artery aneurysm present with occulomotor nerve palsy with or without subarachnoid hemorrhage. Factors associated with a higher likelihood of recovery include time to treatment, partial third nerve deficit, and presence of subarachnoid hemorrhage. Both surgical and endovascular therapy offer a reasonable chance of recovery. Based on level 2 evidence, clipping appears to offer a higher chance of occulomotor nerve palsy recovery; however, coiling will remain as an option particularly in elderly patients or patients with significant comorbidity.
技术进步显著改善了脑动脉瘤的外科手术和血管内治疗。在本文中,我们回顾了关于神经外科医生和介入放射科医生所遇到的最常见颅内动脉瘤之一的治疗的文献。
前床突切除术、临时夹闭、腺苷诱导的心脏停搏和术中血管造影是这些动脉瘤手术夹闭过程中的有用辅助手段。线圈栓塞也是一种有效的治疗选择,尤其在老年人群中。然而,线圈栓塞的后交通动脉瘤复发风险特别高,必须密切随访。就闭塞的完整性和后交通动脉的保留而言,具有细长瘤颈的后交通动脉瘤、真正的后交通动脉瘤以及与胎儿型后交通动脉相关的动脉瘤,手术夹闭可能会有更好的结果。然而,随着血管内技术的进步,后交通动脉瘤的血管内治疗在不久的将来可能会变得等效或更可取。五分之一的后交通动脉瘤患者会出现动眼神经麻痹,伴或不伴有蛛网膜下腔出血。与恢复可能性较高相关的因素包括治疗时间、部分动眼神经功能缺损以及蛛网膜下腔出血的存在。手术和血管内治疗都提供了合理的恢复机会。基于二级证据,夹闭似乎提供了更高的动眼神经麻痹恢复机会;然而,线圈栓塞仍将是一种选择,尤其是在老年患者或有严重合并症的患者中。