[Fe(CN)6]4- 的猝灭不存在并不证明 DNA 插入。

Absence of quenching by [Fe(CN)6]4- is not proof of DNA intercalation.

机构信息

Department of Chemistry, The Ohio State University, Columbus, OH 43210, USA.

出版信息

Chem Commun (Camb). 2011 Feb 14;47(6):1848-50. doi: 10.1039/c0cc04973e. Epub 2011 Jan 4.

PMID:21206938

Abstract

The quenching of the (3)MLCT emission of three Ru(II) complexes of known DNA binding mode is compared. This work shows that relative binding constants dictate whether quenching is observed in the presence of DNA rather than protection of the probe by intercalation, as has been commonly stated.

摘要

比较了三种已知 DNA 结合模式的 Ru(II) 配合物的 (3)MLCT 发射的猝灭情况。这项工作表明，相对结合常数决定了在存在 DNA 的情况下是否观察到猝灭，而不是通常所说的通过嵌入来保护探针。