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寻求人类免疫缺陷病毒感染自愿咨询检测人群中的阿米巴病:病例对照研究。

Amebiasis among persons who sought voluntary counseling and testing for human immunodeficiency virus infection: a case-control study.

机构信息

Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.

出版信息

Am J Trop Med Hyg. 2011 Jan;84(1):65-9. doi: 10.4269/ajtmh.2011.10-0238.

Abstract

This case-control study aimed to characterize the factors associated with amebiasis, defined as presence of anti-Entamoeba histolytica antibody titers of ≧ 128 by indirect hemagglutination assay, among persons seeking voluntary counseling and testing (VCT) for human immunodeficiency virus (HIV) infection. Between April 2006 and September 2009, 57 of 4,802 persons (1.2%) seeking VCT services were seropositive for E. histolytica infection. Compared with 228 seronegative controls, case subjects were older (odds ratio [OR] for per 1-year increase, 1.098; 95% confidence interval [CI], 1.036, 1.165), less likely to hold bachelor degree or higher (OR, 0.359; 95% CI, 0.152, 0.846), and were more likely to be men who have sex with men (MSM) (OR, 8.382; 95% CI, 2.050, 34.266) and have oral-anal sex (OR, 4.016; 95% CI, 1.711, 9.427) in multiple logistic regression analysis. The MSM, fecal-oral contamination, lower educational achievement, and older age were associated with increased risk for amebiasis among persons seeking VCT for HIV infection.

摘要

本病例对照研究旨在描述与阿米巴病相关的因素,阿米巴病定义为间接血凝试验抗体滴度≧128。研究对象为在寻求人免疫缺陷病毒(HIV)感染自愿咨询检测(VCT)服务的人群中,4802 名寻求 VCT 服务者中有 57 人(1.2%)血清抗 Entamoeba histolytica 抗体阳性。与 228 名血清阴性对照者相比,病例组年龄更大(每增加 1 岁的比值比[OR],1.098;95%置信区间[CI],1.036,1.165),获得学士学位或更高学历的可能性更小(OR,0.359;95%CI,0.152,0.846),更有可能是男男性行为者(MSM)(OR,8.382;95%CI,2.050,34.266),肛交(OR,4.016;95%CI,1.711,9.427)。在多因素逻辑回归分析中,MSM、粪口污染、教育程度低和年龄大与 HIV 感染者 VCT 中阿米巴病的风险增加相关。

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