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一项针对社区毒品服务机构中年轻人进行的口腔拭子检测与同日进行血液检测 HIV 感染的随机对照研究。

A randomised controlled study of mouth swab testing versus same day blood tests for HIV infection in young people attending a community drug service.

机构信息

Department of Genito-urinary Medicine, Derbyshire Royal Infirmary, Derby, UK.

出版信息

Drug Alcohol Rev. 2011 Jan;30(1):101-3. doi: 10.1111/j.1465-3362.2010.00208.x.

Abstract

INTRODUCTION AND AIMS

This study was designed to determine whether providing an oral swab test in the community for blood borne virus testing leads to an increase in subsequent attendance for sexually transmitted infection (STI) screening at the STI clinic compared with making appointments for young people to attend the clinic for same day HIV testing and STI screening.

DESIGN AND METHODS

Participants were randomised into either the oral swab test group or the blood test group of the trial if eligible.

RESULTS

All the 27 participants in the oral swab test group were tested for HIV and hepatitis C compared with five for HIV and two for hepatitis C in the blood test group (P < 0.001). Only two of the 27 participants in the blood test group were tested for hepatitis B compared with 25 in the oral swab test group (P < 0.001). Nine participants in the oral swab test group attended the STI clinic for STI screening compared with three in the blood test group (P = 0.09).

DISCUSSION AND CONCLUSIONS

An oral swab test in the community for blood borne virus testing leads to an increase in the number of young high-risk people tested for blood borne infections and is associated with a trend towards higher rates of subsequent attendance for STI screening.

摘要

目的和引言

本研究旨在确定在社区提供口腔拭子检测用于血液传播病毒检测是否会导致随后到性传播感染(STI)诊所进行 STI 筛查的人数增加,与为年轻人预约当天进行 HIV 检测和 STI 筛查相比。

设计和方法

如果符合条件,参与者将被随机分配到口腔拭子检测组或血液检测组参加试验。

结果

与血液检测组的五例 HIV 检测和两例丙型肝炎检测相比,口腔拭子检测组的所有 27 名参与者均接受了 HIV 和丙型肝炎检测(P < 0.001)。与口腔拭子检测组的 25 例相比,只有 2 例血液检测组的参与者接受了乙型肝炎检测(P < 0.001)。与血液检测组的 3 例相比,9 例口腔拭子检测组的参与者到 STI 诊所进行了 STI 筛查(P = 0.09)。

讨论与结论

在社区进行口腔拭子检测用于血液传播病毒检测可增加对血液传播感染的高危年轻人的检测数量,并与随后进行 STI 筛查的比例增加趋势相关。

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