Can Fam Physician. 1992 Sep;38:2143-54.
A critical appraisal of the scientific literature on managing mesconium in labor identified 15 studies which were used to evaluate intervention strategies. Only four were randomized trials: two on the use of amnioinfusion in labor, one on the technique of bulb versus DeLee catheter suction of the newborn, and one on the need for endotracheal intubation and suction in meconium-stained neonates. Current practice is dictated by the most favorable tradeoff between benefit and risk because of limited scientific evidence.
对管理分娩中胎粪的科学文献进行了批判性评估,确定了 15 项用于评估干预策略的研究。其中只有四项是随机试验:两项关于在分娩中使用羊膜腔灌注,一项关于新生儿球囊与 DeLee 导管吸引的技术,一项关于胎粪污染新生儿是否需要气管内插管和吸引的研究。由于科学证据有限,目前的实践是根据利益和风险之间最有利的权衡来决定的。