Cho Kyu-Sup, Kim Hak-Jin, Lee Chang-Hun, Roh Hwan-Jung
Department of Otorhinolaryngology and Medical Research Institute, Pusan National University School of Medicine, Busan, South Korea.
Auris Nasus Larynx. 2011 Aug;38(4):543-6. doi: 10.1016/j.anl.2010.12.005. Epub 2011 Jan 12.
Inflammatory pseudotumor (IPT) originated from the nasopharynx is very rare. To the authors' best knowledge, nasopharyngeal pseudotumor accompanied by abducens nerve palsy due to cavernous sinus invasion has not been reported previously. A 28-year-old male presented with abrupt-onset diplopia and right side severe headache. Physical examination revealed a mild contour bulging mass without mucosal ulceration or necrosis in the nasopharynx. The mass was thought to be a malignant neoplasm such as a carcinoma due to ill-defined, infiltrative tumor extended to the right parapharyngeal, carotid, prevertebral spaces and cavernous sinus on MR images, and hypermetabolic lesion on PET/CT. Histopathology demonstrated inflammatory pseudotumor. The patient was treated with high-dose of oral steroid, and then headache and diplopia was dramatically improved. Although IPT of the nasopharynx is very rare, it is important for otolaryngologists to be aware of this disease process.
起源于鼻咽部的炎性假瘤（IPT）非常罕见。据作者所知，此前尚未有因海绵窦侵犯而伴有展神经麻痹的鼻咽部假瘤的报道。一名28岁男性突发复视和右侧严重头痛。体格检查发现鼻咽部有一轻度轮廓隆起的肿块，无黏膜溃疡或坏死。由于磁共振成像（MR）显示边界不清、浸润性肿瘤延伸至右侧咽旁、颈动脉、椎前间隙和海绵窦，且正电子发射断层显像/计算机断层扫描（PET/CT）显示为高代谢病变，该肿块被认为是一种恶性肿瘤，如癌。组织病理学检查显示为炎性假瘤。患者接受了高剂量口服类固醇治疗，随后头痛和复视明显改善。尽管鼻咽部IPT非常罕见，但耳鼻喉科医生了解这一疾病过程很重要。
