肝移植作为三名纯合子家族性高胆固醇血症兄弟姐妹的一种治疗选择。
Liver transplantation as a treatment option for three siblings with homozygous familial hypercholesterolemia.
作者信息
Küçükkartallar Tevfik, Yankol Yucel, Kanmaz Turan, Topaloğlu Serdar, Acarli Koray, Kalayoglu Munci
机构信息
Department of Organ Transplantation, Istanbul Memorial Hospital, Okmeydani, Istanbul.
出版信息
Pediatr Transplant. 2011 May;15(3):281-4. doi: 10.1111/j.1399-3046.2010.01469.x. Epub 2011 Jan 17.
FH is a hereditary inherited disorder of cholesterol metabolism. Homozygous form of the disease associates severe form of atherosclerotic disease. Clinicians have been tried to inhibit the progression of the homozygous FH with medical and surgical treatment. We here present three siblings with homozygous FH who were successfully treated with liver transplantation.
家族性高胆固醇血症（FH）是一种遗传性胆固醇代谢紊乱疾病。该疾病的纯合子形式与严重的动脉粥样硬化疾病相关。临床医生一直试图通过药物和手术治疗来抑制纯合子FH的进展。我们在此报告三名患有纯合子FH的兄弟姐妹，他们通过肝移植成功得到治疗。
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