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内科出院时的药物差异。

Medication discrepancies at discharge from an internal medicine service.

机构信息

Service of Internal Medicine-Los Montalvos, University Hospital of Salamanca, Los Montalvos s/n, 37192 Salamanca, Spain.

出版信息

Eur J Intern Med. 2011 Feb;22(1):43-8. doi: 10.1016/j.ejim.2010.10.003. Epub 2010 Nov 11.

Abstract

BACKGROUND

Medication errors most commonly occur at the time of medication prescribing and particularly at the moment of the transitions of care. The objectives of this study were to identify and characterize the discrepancies between the physicians' discharge medication orders and the medication lists at admission obtained by an internal medicine specialist physician in a general internal medicine service.

METHODS

This descriptive, retrospective, study was carried out at a tertiary care university teaching hospital in Spain. It was based on the review of non selected, consecutive, hospital discharge reports. Discrepancies were identified, categorized and characterized through the analysis of the information (medication lists, laboratory tests results, diagnosis, and clinical evolution) contained in them.

RESULTS

We analyzed 954 discharge reports. In the medication reconciliation process, we find discrepancies in 832 (87.2%) of them. Justified discrepancies were found in 828 (86.8%) reports and unjustified discrepancies in 52 (5.4%). Omission of a medication was the most frequent medication error detected in 86.4% of cases, followed by incomplete prescription (9.6%). The number of diagnosis, the length of hospital stay and the number of permanent medications at admission were the characteristics of cases associated with medication discrepancies in multivariate linear regression (P<0.01).

CONCLUSIONS

Although considering the limitations in its design, it is remarkable the low number of medication errors detected in our study. Appropriate routines to ensure an accurate medication history collection and a methodical elaboration of the medication list at discharge, when performed by trained internists, are important for an adequate medication reconciliation process.

摘要

背景

药物错误最常发生在开出处方时,尤其是在转院的那一刻。本研究的目的是确定并描述内科专家医师在普通内科病房获得的入院时药物清单与医生出院药物医嘱之间的差异。

方法

这是一项在西班牙一家三级护理教学医院进行的描述性、回顾性研究。它基于对非选择性、连续的住院出院报告的审查。通过分析其中包含的信息(药物清单、实验室检查结果、诊断和临床演变)来识别、分类和描述差异。

结果

我们分析了 954 份出院报告。在药物核对过程中,我们发现其中 832 份(87.2%)存在差异。在 828 份(86.8%)报告中发现了合理的差异,而在 52 份(5.4%)报告中发现了不合理的差异。漏用药物是最常见的药物错误,在 86.4%的病例中发现,其次是处方不完整(9.6%)。多变量线性回归显示,病例的特征包括诊断数量、住院时间长短和入院时的永久性药物数量与药物差异有关(P<0.01)。

结论

尽管存在设计上的限制,但在我们的研究中发现药物错误的数量很少,这一点值得注意。适当的常规操作可以确保准确地收集药物史,并由经过培训的内科医师有条理地制定出院时的药物清单,这对于适当的药物核对过程非常重要。

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