Nevoux Jérôme, Roger Gilles, Chauvin Pierre, Denoyelle Françoise, Garabédian Erea Noel
UMPC, Univ Paris, France.
Arch Otolaryngol Head Neck Surg. 2011 Jan;137(1):24-9. doi: 10.1001/archoto.2010.229.
To assess the efficacy of partial ossicular chain reconstruction using autologous cartilage.
Prospective study (April 1, 1997, through January 1, 2008).
Tertiary academic children's hospital.
Two hundred forty-eight children (268 ears) underwent partial ossicular chain reconstruction using a shaped block of tragal cartilage interposed between the head of the stapes and an underlay tympanic membrane reconstruction along with tragal cartilage and its perichondrium.
Anatomical and audiologic results were evaluated according to the American Academy of Otolaryngology-Head and Neck Surgery guidelines. χ² Tests and multivariate analysis were used for statistical evaluation.
Mean age at surgery was 10.9 years. Single-stage surgery was performed in 124 ears (46.3%) (62.9% for cholesteatomas and 32.3% for retraction pockets). Second-look patients (53.7%) included 93.8% of staged surgery. Audiometric results were available for 222 ears at 1 year and for 78 ears at 5 years. Closure of the average air-bone gap (ABG) to within 20 dB was achieved in 62.2% of ears at 1 year. The mean (SD) preoperative and 1-year postoperative ABGs were 25 (11.8) dB and 18.9 (10.3) dB, respectively. Anatomical results were satisfactory in 87.3%. No cases of extrusion, resorption, or displacement of the cartilage were encountered. No statistically significant difference was found between audiometric results at 1 and 5 years. Multivariate analysis showed a significant negative correlation between preoperative and postoperative ABGs and between postoperative otitis media with effusion and postoperative ABG (P < .05).
Cartilage ossiculoplasty is a reliable technique for partial ossicular replacement. Long-term hearing outcomes remain stable and satisfactory. Preoperative ABG and postoperative otitis media are the predictive factors of the hearing outcome.
评估自体软骨用于部分听骨链重建的疗效。
前瞻性研究(1997年4月1日至2008年1月1日)。
三级学术儿童医院。
248名儿童(268耳)接受了部分听骨链重建,使用一块塑形的耳屏软骨置于镫骨头与鼓膜夹层重建之间,同时使用耳屏软骨及其软骨膜。
根据美国耳鼻咽喉头颈外科学会指南评估解剖学和听力学结果。采用χ²检验和多变量分析进行统计学评估。
手术时的平均年龄为10.9岁,124耳(46.3%)进行了一期手术(胆脂瘤患者中62.9%,内陷袋患者中32.3%)。二次探查患者(53.7%)包括93.8%的分期手术患者。1年时222耳、5年时78耳有听力测定结果。1年时62.2%的耳平均气骨导间距(ABG)缩小至20 dB以内。术前和术后1年的平均(标准差)ABG分别为25(11.8)dB和18.9(10.3)dB。解剖学结果在87.3%的患者中令人满意。未遇到软骨挤出、吸收或移位的病例。1年和5年的听力学结果之间未发现统计学显著差异。多变量分析显示术前和术后ABG之间以及术后分泌性中耳炎与术后ABG之间存在显著负相关(P <.05)。
软骨听骨成形术是一种可靠的部分听骨置换技术。长期听力结果保持稳定且令人满意。术前ABG和术后中耳炎是听力结果的预测因素。