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肥胖症患者接受开放式减肥手术全身麻醉期间腹部开放对呼吸力学的影响。

The effects of abdominal opening on respiratory mechanics during general anaesthesia for open bariatric surgery in morbidly obese patients.

作者信息

Gaszyński Tomasz M

机构信息

Department of Anaesthesiology and Intensive Therapy, Medical University of Lodz, Poland.

出版信息

Anestezjol Intens Ter. 2010 Oct-Dec;42(4):172-4.

Abstract

BACKGROUND

Morbid obesity BMI 40 kg mL-2 is associated with several changes in anatomy and physiology of the respiratory system. Respiratory work is increased whereas compliance of the chest wall and lungs is decreased. Increased intra-abdominal pressure compresses the diaphragm and reduces its movability. Abdominal opening should influence respiratory mechanics.

METHODS

Forty-seven morbidly obese patients (BMI 49.54 ± 7.21 kg m-2) scheduled for elective bariatric surgery (open Roux-en-Y-Gastric Bypass - RYGB) were included in the study and divided into 3 groups: 40< BMI <50, 50< BMI <60 and BMI >60. Measurements were performed during general anaesthesia at two time points: before (T1) and after abdominal opening (T2). All patients were ventilated using the volume control mode.

RESULTS

Preoperative spirometry revealed significantly decreased FEV 1% in the BMI >60 group. The conditions of mechanical ventilation during general anaesthesia deteriorated with an increasing BMI. After abdominal opening,the mechanical ventilation conditions improved: increased lung compliance and decreased airway pressures. The difference was statistically significant in the entire population studied. After dividing the population into groups, however, the difference was no longer significant in patients with BMI >60. The most significant difference in peak and plateau pressures after abdominal opening was observed in patients with BMI <50.

CONCLUSION

Abdominal opening improves the conditions of mechanical ventilation in morbidly obese patients; when BMI is over 60 kg m-2, this improvement may not be relevant.

摘要

背景

病态肥胖(体重指数[BMI]≥40kg/m²)与呼吸系统的解剖学和生理学的若干变化相关。呼吸功增加,而胸壁和肺的顺应性降低。腹内压升高会压迫膈肌并降低其活动度。腹部开放应会影响呼吸力学。

方法

本研究纳入了47例计划接受择期减肥手术(开放式Roux-en-Y胃旁路术[RYGB])的病态肥胖患者(BMI为49.54±7.21kg/m²),并将其分为3组:40<BMI<50、50<BMI<60和BMI>60。在全身麻醉期间的两个时间点进行测量:腹部开放前(T1)和腹部开放后(T2)。所有患者均采用容量控制模式通气。

结果

术前肺活量测定显示,BMI>60组的第1秒用力呼气量百分比(FEV₁%)显著降低。全身麻醉期间机械通气的状况随着BMI的增加而恶化。腹部开放后,机械通气状况改善:肺顺应性增加,气道压力降低。在整个研究人群中,差异具有统计学意义。然而,将人群分组后,BMI>60的患者中差异不再显著。腹部开放后,BMI<50的患者在峰值压力和平台压力方面的差异最为显著。

结论

腹部开放可改善病态肥胖患者的机械通气状况;当BMI超过60kg/m²时,则可能无此改善效果。

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