Kuramoto Women's Clinic, Fukuoka, Japan.
Fertil Steril. 2011 Jun 30;95(8):2648-50. doi: 10.1016/j.fertnstert.2010.12.038. Epub 2011 Jan 22.
We evaluated our clinical data on refrozen-thawed ETs (92 cycles) and found that human embryos were capable of withstanding two freeze-thaw cycles, resulting in normal live births after transfer at a rate similar to that of primary frozen-thawed embryos. This is the first follow-up study to present perinatal outcomes of children born after embryo re-cryopreservation, and our results should encourage clinicians to explore the possibility of performing the refreezing procedure.
我们评估了我们关于复融胚胎移植(92 个周期)的临床数据,发现人类胚胎能够承受两次冷冻-解冻循环,在进行移植后活产率与原发性冷冻-解冻胚胎相似。这是首例报道胚胎复融后出生儿童围产期结局的随访研究,我们的结果应该鼓励临床医生探索进行复融程序的可能性。