[普通外科和内脏外科中基于证据的抗生素预防]

[Evidence-based antibiotic prophylaxis in general and visceral surgery].

作者信息

Knebel P, Weigand M A, Büchler M W, Seiler C M

机构信息

Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 110, Heidelberg, Germany.

出版信息

Chirurg. 2011 Mar;82(3):227-34. doi: 10.1007/s00104-010-2011-6.

DOI:10.1007/s00104-010-2011-6

PMID:21258773

Abstract

The use of prophylactic perioperative antibiotic therapy if indicated could successfully and safely prevent surgical wound infections. The current guidelines (S1) for prophylactic perioperative antibiotic therapy of the Study Group of the Scientific Medical Associations (AWMF) of 2004 was replaced by a recommendation of the study group of the Paul-Ehrlich-Gesellschaft for Chemotherapy (PEG) in 2010. This recommendation includes recent research data from 2000 to 2008. Indications and choice of antibiotic agent depend on specific risk factors of the patient and the operation performed. The aim of this article is to describe the current recommendations of the PEG for general and visceral surgery.

摘要

如果有指征，使用围手术期预防性抗生素治疗可成功且安全地预防手术伤口感染。2004年科学医学协会研究小组（AWMF）关于围手术期预防性抗生素治疗的现行指南（S1）于2010年被保罗·埃尔利希化疗协会（PEG）研究小组的一项建议所取代。该建议纳入了2000年至2008年的最新研究数据。抗生素的指征和选择取决于患者的特定风险因素及所实施的手术。本文旨在描述PEG对普通外科和内脏外科的现行建议。