Department of Gastroenterology, Leeds General Infirmary, Great George Street, Leeds, UK.
Aliment Pharmacol Ther. 2011 Apr;33(7):768-81. doi: 10.1111/j.1365-2036.2010.04573.x. Epub 2011 Jan 24.
Gastric acid has an important pathophysiological role in human beings. Numerous methods have been evaluated over the years in an attempt to measure gastric acid and stomach acidity, to study the role of gastric acid in gastrointestinal diseases in humans and to evaluate the effects of acid suppressing drugs.
To review methods that have been used to measure gastric acid and gastric acidity.
Searches of the electronic databases PUBMED, MEDLINE and EMBASE, were performed with articles restricted to English language and human subjects. References were also identified from the bibliographies of selected articles.
Methods for measuring gastric acid include both invasive and non-invasive techniques. Invasive tests include the conventional gastric acid aspiration tests, gastric pH measurement techniques and endoscopic methods. Non-invasive methods use urinary analysis, breath analysis, serum pepsinogens assay, scintigraphic techniques, impedence tomography and alkaline tide for measurement of gastric acid.
Several methods of measuring gastric acid exist. Invasive tube tests are uncomfortable and time consuming, whereas most of the non-invasive methods are at best semiquantitative and useful in detecting low or absent acid secretion. Further attempts to explore new methods for measuring gastric acid are therefore warranted.
胃酸在人体中有重要的病理生理学作用。多年来，人们评估了许多方法来测量胃酸和胃酸度，以研究胃酸在人类胃肠道疾病中的作用，并评估抑酸药物的效果。
综述用于测量胃酸和胃酸度的方法。
在 PUBMED、MEDLINE 和 EMBASE 电子数据库中进行检索，文章限定为英文和人类研究对象。还从选定文章的参考文献中确定了参考文献。
测量胃酸的方法包括有创和非侵入性技术。有创性检查包括传统的胃酸抽吸检查、胃 pH 值测量技术和内镜方法。非侵入性方法使用尿分析、呼气分析、血清胃蛋白酶原测定、闪烁照相技术、阻抗断层成像和碱潮来测量胃酸。
有几种测量胃酸的方法。有创性管检查既不舒服又耗时，而大多数非侵入性方法最多只能进行半定量检测，并且只能用于检测低胃酸或无胃酸分泌。因此，有必要进一步尝试探索新的胃酸测量方法。
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