Professor of Haematology and Head of School of Medicine and Dentistry, Polwarth, Foresterhill, Aberdeen AB252ZD, Scotland.
Thromb Res. 2011 Feb;127 Suppl 3:S47-50. doi: 10.1016/S0049-3848(11)70013-5.
Although the typical thrombotic manifestations of antiphospholipid syndrome, and pregnancy complications, are well recognised, the literature is awash with reports of more obscure associations and apparent complications. Some occur sufficiently frequently to be regarded as occasional features of the syndrome, whereas in other instances there remains doubt about any pathogenic role for antiphospholipid antibodies. The distinction is important as wrong assumptions may lead to failure to seek alternative diagnoses and the implementation of inappropriate treatments.
虽然抗磷脂综合征的典型血栓表现和妊娠并发症已得到广泛认识,但文献中充斥着更多不常见的关联和明显并发症的报告。有些情况发生的频率足够高,可被视为该综合征的偶发特征,而在其他情况下,抗磷脂抗体是否具有致病作用仍存在疑问。这种区别很重要,因为错误的假设可能导致未能寻求其他诊断和实施不适当的治疗。