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系统性硬皮病表现为充血性心力衰竭:一例尸检病例。

Systemic sclerosis presented as congestive heart failure: an autopsy case.

机构信息

Department of Pathology, Iwate Medical University School of Medicine, 19-1 Uchimaru, Morioka, 020-8505, Japan.

出版信息

Mod Rheumatol. 2011 Aug;21(4):423-7. doi: 10.1007/s10165-011-0413-z. Epub 2011 Jan 25.

Abstract

We report the autopsy results of a patient with systemic sclerosis with myositis lesions in the skeletal muscles and myocardium. A 69-year-old Japanese woman developed congestive heart failure and died due to respiratory failure with restrictive hypoventilation. The heart at autopsy showed dilated ventricular hypertrophy, and histopathology of the heart exhibited diffuse replacement fibrosis resembling the lesion of ischemic heart diseases in addition to patchy fibrosis around myocardial fibers suggesting post-myocarditis-like fibrosis.

摘要

我们报告了一例系统性硬化症伴骨骼肌和心肌肌炎病变患者的尸检结果。一名 69 岁日本女性因心力衰竭导致呼吸衰竭和限制性低通气而死亡。尸检心脏显示扩张性心室肥厚,心脏组织病理学表现为弥漫性替代纤维化,类似于缺血性心脏病的病变,此外还有心肌纤维周围的斑片状纤维化,提示类似于心肌炎后的纤维化。

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