Department of Epidemiology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8558, Japan.
J Occup Environ Med. 2011 Feb;53(2):124-6. doi: 10.1097/JOM.0b013e3182099175.
Evidence linking short-term exposure to outdoor air pollution with hemorrhagic stroke is inconsistent.
We evaluated the associations between outdoor air pollution and specific types of stroke in Tokyo, Japan, from April 2003 to December 2008. We obtained daily counts of stroke mortality (n = 41,440) and concentrations of nitrogen dioxide as well as particles less than 2.5 μm in diameter. Time-series analysis was employed.
Although same-day air pollutants were positively associated with ischemic stroke and intracerebral hemorrhage mortality, both air pollutants were more strongly associated with subarachnoid hemorrhage mortality: rate ratio was 1.041 (95% confidence interval: 1.011-1.072) for each 10 μg/m3 increase in the previous-day particles less than 2.5 μm.
This study suggests that short-term exposure to outdoor air pollution increases the risks of hemorrhagic stroke mortality as well as ischemic stroke mortality.
户外空气污染与出血性中风之间的短期暴露关联证据并不一致。
我们评估了 2003 年 4 月至 2008 年 12 月期间日本东京户外空气污染与特定类型中风之间的关联。我们获得了中风死亡率（n=41440）的每日计数以及二氧化氮和直径小于 2.5μm 的颗粒浓度。采用时间序列分析。
尽管当日的空气污染物与缺血性中风和脑出血死亡率呈正相关，但两种空气污染物与蛛网膜下腔出血死亡率的关联更强：前一天每增加 10μg/m3 小于 2.5μm 的颗粒，死亡率比为 1.041（95%置信区间：1.011-1.072）。
这项研究表明，短期暴露于户外空气污染会增加出血性中风死亡率以及缺血性中风死亡率的风险。
