治疗急性双相抑郁症的抗抑郁药替代疗法。

Alternatives to antidepressants in treating acute bipolar depression.

机构信息

Department of Psychiatry, Harvard Medical School and Massachusetts General Hospital, Boston, MA, USA.

出版信息

J Clin Psychiatry. 2011 Jan;72(1):e03. doi: 10.4088/JCP.9075tx3c.

Abstract

Major depressive episodes and subsyndromal depressive symptoms are associated with significant psychosocial impairment for patients with bipolar disorder. However, insufficient evidence exists to support the efficacy of antidepressants for treating bipolar depression. Alternative pharmacotherapies have been approved for the treatment of bipolar depressive episodes, and adjunctive psychosocial interventions have proven efficacy when used with pharmacotherapy.

摘要

重度抑郁发作和亚综合征抑郁症状与双相情感障碍患者的显著社会心理功能损害相关。然而，目前尚缺乏足够的证据支持抗抑郁药治疗双相抑郁的疗效。有其他的一些药物疗法已被批准用于治疗双相抑郁发作，并且当与药物治疗联合使用时，辅助心理社会干预措施已被证明是有效的。