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1986 年至 2007 年加拿大最大成人创伤中心的头部损伤流行病学趋势。

The epidemiological trends of head injury in the largest Canadian adult trauma center from 1986 to 2007.

机构信息

Division of Neurosurgery, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada.

出版信息

J Neurosurg. 2011 Jun;114(6):1502-9. doi: 10.3171/2010.12.JNS10808. Epub 2011 Jan 28.

Abstract

OBJECT

This study documents the epidemiology of head injury over the course of 22 years in the largest Level I adult trauma center in Canada. This information defines the current state, changing pattern, and relative distribution of demographic factors in a defined group of trauma patients. It will aid in hypothesis generation to direct etiological research, administrative resource allocation, and preventative strategies.

METHODS

Data on all the trauma patients treated at Sunnybrook Health Sciences Centre (SHSC) from 1986 to 2007 were collected in a consecutive, prospective fashion. The authors reviewed these data from the Sunnybrook Trauma Registry Database in a retrospective fashion. The aggregate data on head injury included demographic data, cause of injury, and Injury Severity Score (ISS). The collected data were analyzed using univariate techniques to depict the trend of variables over years. The authors used the length of stay (LOS) and number of deaths per year (case fatality rate) as crude measures of outcome.

RESULTS

A total of 16,678 patients were treated through the Level I trauma center at SHSC from January 1986 to December 2007. Of these, 9315 patients met the inclusion criteria (ISS > 12, head Abbreviated Injury Scale score > 0). The median age of all trauma patients was 36 years, and 69.6% were male. The median ISS of the head-injury patients was 27. The median age of this group of patients increased by 12 years over the study period. Motorized vehicle accidents accounted for the greatest number of head injuries (60.3%) although the relative percentage decreased over the study period. The median transfer time of patients sustaining a head injury was 2.58 hours, and there was an approximately 45 minute improvement over the 22-year study period. The median LOS in our center decreased from 19 to 10 days over the study period. The average case fatality rate was 17.4% over the study period. In multivariate analysis, more severe injuries were associated with increased LOS as was increasing time from injury to hospital presentation. Age and injury severity were independently predictive of mortality.

CONCLUSIONS

These data will provide useful information to guide future studies on the changing patterns of head injury, possible mechanisms of injury, and efficient resource allocation for management of this condition.

摘要

目的

本研究记录了加拿大最大的一级成人创伤中心 22 年来的头部损伤流行病学。这些信息定义了特定创伤患者群体中人口统计学因素的当前状态、变化模式和相对分布。它将有助于生成假说,以指导病因研究、行政资源分配和预防策略。

方法

以连续、前瞻性的方式收集了 1986 年至 2007 年期间在 Sunnybrook 健康科学中心 (SHSC) 治疗的所有创伤患者的数据。作者以回顾性的方式从 Sunnybrook 创伤登记数据库中审查了这些数据。汇总的头部损伤数据包括人口统计学数据、损伤原因和损伤严重程度评分 (ISS)。使用单变量技术分析收集的数据,以描绘多年来变量的趋势。作者使用住院时间 (LOS) 和每年死亡人数(病死率)作为结果的粗略衡量标准。

结果

1986 年 1 月至 2007 年 12 月,共有 16678 名患者在 SHSC 的一级创伤中心接受治疗。其中,9315 名患者符合纳入标准(ISS > 12,头部简明损伤量表评分 > 0)。所有创伤患者的中位年龄为 36 岁,男性占 69.6%。头部损伤患者的中位 ISS 为 27。在研究期间,该组患者的中位年龄增加了 12 岁。机动车事故导致的头部损伤数量最多(60.3%),但在研究期间相对比例有所下降。头部损伤患者的中位转运时间为 2.58 小时,在 22 年的研究期间大约改善了 45 分钟。在研究期间,我们中心的中位住院时间从 19 天减少到 10 天。平均病死率为 17.4%。在多变量分析中,伤势越严重,住院时间越长,从受伤到医院就诊的时间越长。年龄和损伤严重程度是死亡率的独立预测因素。

结论

这些数据将为指导关于头部损伤变化模式、可能的损伤机制以及这种情况的有效资源分配的未来研究提供有用信息。

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