Can Fam Physician. 1981 Oct;27:1615-24.
Basal ganglia side effects caused by the neuroleptic drugs include the acute extrapyramidal syndromes (dystonias, akathisia and parkinsonism) and tardive dyskinesia. These may be ignored, misdiagnosed or mistreated by the patient or physician. Because the neuroleptics are effective in the treatment and secondary prevention of serious psychiatric disorders such as schizophrenia, it is important that neurological side effects be anticipated and appropriately managed. This increases patient compliance and enhances the therapeutic relationship. Patients should be examined frequently and systematically for basal ganglia side effects. (Can Fam Physician 1981; 27:1615-1624).
神经安定药引起的基底节副作用包括急性锥体外综合征(张力障碍、静坐不能和帕金森病)和迟发性运动障碍。这些可能会被患者或医生忽视、误诊或误治。由于神经安定药在治疗和二级预防精神疾病如精神分裂症等严重疾病方面非常有效,因此预测和适当处理神经副作用非常重要。这可以提高患者的依从性,增强治疗关系。应经常系统地检查患者的基底节副作用。(《加拿大家庭医生》1981;27:1615-1624)