School of Social and Community Medicine, University of Bristol, Bristol, UK.
J Affect Disord. 2011 Jun;131(1-3):104-12. doi: 10.1016/j.jad.2011.01.002. Epub 2011 Feb 5.
Poor school performance and low IQ are associated with an increased risk of suicide in males; it is uncertain whether cognitive performance is a risk factor for suicide in females and whether severe mental illness influences these associations.
Record linkage study of Swedish education, population and census data with mortality and inpatient registers. Data were available for 95,497 males and 91,311 females born in 1972 and 1977 and followed up until 31 December 2005.
230 males and 90 females died from suicide over the follow-up period. There were strong inverse associations between school performance at age 16 and subsequent suicide risk in males (fully adjusted hazard ratio (HR) per SD increase in school performance score: 0.6 (95% CI 0.6 to 0.7; p < 0.001)) but not females: adjusted HR. 1.1 (CI 0.9 to 1.4 p = 0.50). In males there were almost four fold differences in suicide risk between children in the top and bottom fifths of the range of school grade scores. Similar associations were seen with upper secondary school performance (age 18/19 years). There was no strong evidence that deterioration in school performance between ages 16 and 18 was associated with increased suicide risk. Amongst men who developed severe psychiatric illness school performance was not associated with suicide risk.
We had limited information on the prevalence of minor psychiatric disorder in cohort members and no data on IQ for the cohort as a whole.
Good performance in secondary (age 16) and upper secondary (age 18) school is associated with a reduced risk of suicide in men but not women. This protective effect is not seen amongst those who develop severe psychiatric illness. These differences indicate that the aetiology of suicide differs in males and females and in those with and without severe mental illness.
学业表现不佳和智商较低与男性自杀风险增加相关;目前尚不清楚认知表现是否是女性自杀的风险因素,以及严重精神疾病是否会影响这些关联。
对瑞典教育、人口和人口普查数据与死亡率和住院登记数据进行记录链接研究。数据可用于 1972 年和 1977 年出生的 95497 名男性和 91311 名女性,随访至 2005 年 12 月 31 日。
在随访期间,有 230 名男性和 90 名女性死于自杀。在男性中,16 岁时的学业成绩与随后的自杀风险呈强烈负相关(按学业成绩评分每增加一个标准差进行的完全调整后的危险比(HR):0.6(95%CI 0.6 至 0.7;p<0.001)),但在女性中则没有:调整后的 HR 为 1.1(95%CI 0.9 至 1.4,p=0.50)。在男性中,处于学业成绩评分范围最高和最低五分位的儿童之间的自杀风险差异几乎相差四倍。在高中(18 岁/19 岁)表现也存在类似的关联。在 16 岁至 18 岁之间学业成绩下降与自杀风险增加之间没有强有力的证据。在患有严重精神疾病的男性中,学业成绩与自杀风险无关。
我们对队列成员中小型精神障碍的患病率信息有限,并且整个队列的智商数据也没有。
在男性中,中学(16 岁)和高中(18 岁)的良好表现与自杀风险降低相关,但在女性中则不然。这种保护作用在患有严重精神疾病的人群中并不明显。这些差异表明,自杀的病因在男性和女性以及患有和不患有严重精神疾病的人群中存在差异。