台湾黄牛木茎中的氧杂蒽酮和二苯甲酮糖苷。

Xanthone and benzophenone glycosides from the stems of Cratoxylum formosum ssp. pruniflorum.

作者信息

Duan Ying-hui, Dai Yi, Wang Guang-hui, Chen Hai-feng, Gao Hao, Chen Jie-bo, Yao Xin-sheng, Zhang Xiao-kun

机构信息

College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.

出版信息

Chem Pharm Bull (Tokyo). 2011;59(2):231-4. doi: 10.1248/cpb.59.231.

DOI:10.1248/cpb.59.231

PMID:21297304

Abstract

Two new xanthone glycosides, namely pruniflorosides A and B (1, 2), a new benzophenone glycoside, prunifloroside C (3), and a new xanthone, pruniflorone S (4) were isolated from the stems of Cratoxylum formosum ssp. pruniflorum, along with six known xanthones (5-10). Their structures were determined on the basis of extensive spectroscopic analysis. In addition, their retinoid X receptor α (RXRα) transcriptional activities were evaluated in vitro.

摘要

从台湾黄牛木（Cratoxylum formosum ssp. pruniflorum）的茎中分离出两种新的氧杂蒽酮苷，即李叶黄牛木苷A和B（1, 2）、一种新的二苯甲酮苷李叶黄牛木苷C（3）以及一种新的氧杂蒽酮李叶黄牛木酮S（4），同时还分离出六种已知的氧杂蒽酮（5 - 10）。通过广泛的光谱分析确定了它们的结构。此外，还在体外评估了它们对维甲酸X受体α（RXRα）的转录活性。