Skotnicka Bozena, Hassmann-Poznańska Elzbieta
Klinika Otolaryngologii Dzieciecej UM w Białymstoku.
Otolaryngol Pol. 2010 Nov-Dec;64(6):375-81. doi: 10.1016/S0030-6657(10)70590-4.
Children cholesteatoma have been shown to demonstrate aggressive growth with greater extension and higher rates residual and recurrent disease compared with adults, due to anatomic and physiologic differences.
This study aimed to determine the clinical and pathological features of cholesteatoma in young children less than 7 years of age.
Retrospective review of a group of 23 children (24 ears) who had cholesteatoma surgery between 1996 and 2004. Patients ages ranged from 1.8 to 7 years, follow up from 3.5 to 12 years (mean 7.4). Medical history (previous otorrhea, hearing loss) and contralateral ear status was analyzed. The extent of cholesteatoma and ossicular destruction for attic, pars tensa I and pars tensa II type and congenital of cholesteatoma was graded using of Saleh and Mills classification. Residual and recurrent disease depending on type of cholesteatoma, extent of the disease, type of surgery and contalateral ear status was assessed.
Otorrhea and hearing loos are the most common clinical symptoms observed in 90% and 59% children. 70% of treated children had otitis media with effusion and/or its sequel in contralateral ear. 60% of acquired cholesteatomas were classified as S3 and S4 extension during surgery with ossicular destruction in 46% of attic cholestatoma. 75% operated ears had a signs of mucosa inflammation during surgery. Residual cholesteatoma was observed in 38.5% ears with attic cholesteatoma and in 25% with pars tensa I cholesteatoma.
Acquired cholesteatoma in young children are diagnosed in the advanced stages with ossicular chain destruction. High rate of recidivism after surgery, particularly in attic cholesteatomas is observed. Most of operated ears have symptoms of inflammation of middle era mucosa during surgery and otitis media with effusion in contralateral ear and because of that need long-term follow up and constant observation.
由于解剖学和生理学差异,与成人相比,儿童胆脂瘤表现出侵袭性生长,病变范围更广,残留和复发性疾病发生率更高。
本研究旨在确定7岁以下幼儿胆脂瘤的临床和病理特征。
回顾性分析1996年至2004年间接受胆脂瘤手术的23例儿童(24耳)。患者年龄在1.8至7岁之间,随访时间为3.5至12年(平均7.4年)。分析病史(既往耳漏、听力损失)和对侧耳情况。使用Saleh和Mills分类法对胆脂瘤的范围以及上鼓室、紧张部I型和紧张部II型胆脂瘤及先天性胆脂瘤的听骨链破坏情况进行分级。根据胆脂瘤类型、病变范围、手术类型和对侧耳情况评估残留和复发性疾病。
耳漏和听力下降是最常见的临床症状,分别在90%和59%的儿童中出现。70%接受治疗的儿童对侧耳患有分泌性中耳炎和/或其后遗症。60%的后天性胆脂瘤在手术期间被分类为S3和S4期扩展,46%的上鼓室胆脂瘤存在听骨链破坏。75%的手术耳在手术期间有黏膜炎症迹象。在上鼓室胆脂瘤耳中,38.5%观察到残留胆脂瘤,紧张部I型胆脂瘤耳中为25%。
幼儿后天性胆脂瘤在晚期被诊断出来,伴有听骨链破坏。手术后复发率高,尤其是在上鼓室胆脂瘤中。大多数手术耳在手术期间有中耳黏膜炎症症状,对侧耳有分泌性中耳炎,因此需要长期随访和持续观察。