治疗：脾酪氨酸激酶抑制剂——类风湿关节炎的新疗法？
Therapy: Spleen tyrosine kinase inhibitors--novel therapies for RA?
机构信息
Arthritis Unit, Department of Rheumatology, Hospital Clínic, Villarroel 170, Barcelona, Spain.
出版信息
Nat Rev Rheumatol. 2011 Mar;7(3):134-6. doi: 10.1038/nrrheum.2011.8. Epub 2011 Feb 8.
PMID:21304505
Abstract
In patients with active rheumatoid arthritis despite therapy with DMARDS, treatment with a spleen tyrosine kinase inhibitor has achieved similar response rates to those achieved in clinical trials of other drugs, including biologic agents. Where might these agents fit in the current armamentarium against this disease?
摘要
在接受 DMARDs 治疗但仍处于活动期的类风湿关节炎患者中，使用脾酪氨酸激酶抑制剂治疗可获得与临床试验中其他药物（包括生物制剂）相似的反应率。这些药物在当前针对这种疾病的武器库中可能会有什么作用？
Zotero 插件