Menif Khaled, Bouziri Asma, Ben Jaballah Najla
Universite Tunis, El Manar, Tunisie.
Tunis Med. 2011 Feb;89(2):132-5.
The pediatric septic shock mortality in Tunisia remains high (50%) and was markedly higher than in western countries (10%). The decrease in septic shock mortality has been obtained with the advent of the early goal directed therapy.
The aim of this paper is to propose to the first line practitioners in Tunisia, during the first hour after establishing the diagnosis of septic shock practical clinical guidelines based on earlier consensus recommendations.
Literature review.
Septic shock must be rapidly suspected and early recognized. Adequate oxygenation and prompt correction of hemodynamic derangements has been shown to improve outcome through aggressive volume resuscitation, early empiric antibiotherapy and early initiation of vasopressor agents. Frequent reassessment has been emphasized to ensure appropriate management. This treatment must take into consideration the resources available in our area. We can reasonably hope to decrease mortality of patients with septic shock if the first line physicians keep in mind specific therapeutic goals.
突尼斯小儿脓毒性休克死亡率仍然很高(50%),明显高于西方国家(10%)。随着早期目标导向治疗的出现,脓毒性休克死亡率有所下降。
本文旨在根据早期的共识性建议,为突尼斯的一线从业者在诊断脓毒性休克后的第一小时内提出实用的临床指南。
文献综述。
必须迅速怀疑并早期识别脓毒性休克。通过积极的容量复苏、早期经验性抗生素治疗和早期启动血管活性药物,充分的氧合和迅速纠正血流动力学紊乱已被证明可改善预后。强调要经常重新评估以确保适当的管理。这种治疗必须考虑到我们地区现有的资源。如果一线医生牢记特定的治疗目标,我们有理由希望降低脓毒性休克患者的死亡率。