Gassab Elyes, Krifa Nesrine, Sayah Najoua, Khaireddine Noura, Koubaa Jamel, Gassab Aicha
Universit de Monastir, Tunisie.
Tunis Med. 2011 Feb;89(2):151-6.
Necrotizing otitis externa is a potentially lethal form of otitis externa which occurs mainly in elderly diabetic.
To study the clinical, diagnostic and therapeutic aspects of necrotizing otitis externa and to describe the outcomes of this disease.
We report in this retrospective study, a series of 36 patients treated in our department for necrotizing otitis externa over a period of 9 years.
Our series consisted of 34 diabetics. The average age of our patients was 62 years. The diagnosis was based on clinical, biological and bacteriological data and on imaging findings. A medical treatment based on a systemic antibiotic therapy combining a third generation cephalosporin to a fluoroquinolone was prescribed in 24 cases and to an aminoglycoside in 12 cases. In addition, a local treatment was performed daily and included meticulous cleaning of the external auditory canal and topical application of antimicrobial agents. Surgical debridement of infected soft tissues and bone sequestra was indicated in 8 cases because of the lack of improvement with medical treatment. Only one patient underwent hyperbaric oxygen therapy. The cure rate was estimated at 86%. Only one death was noted.
Necrotizing otitis externa is a severe infection. Its prognosis has improved markedly since the advent of antibiotics effective on Pseudomonas aeruginosa. Its management must be started without delay and its treatment must be prolonged.
坏死性外耳道炎是一种潜在致命性的外耳道炎形式,主要发生于老年糖尿病患者。
研究坏死性外耳道炎的临床、诊断及治疗方面,并描述该疾病的治疗结果。
在这项回顾性研究中,我们报告了9年间在我科接受治疗的36例坏死性外耳道炎患者。
我们的病例系列包括34例糖尿病患者。患者的平均年龄为62岁。诊断基于临床、生物学、细菌学数据及影像学检查结果。24例患者采用第三代头孢菌素联合氟喹诺酮类药物的全身抗生素治疗方案,12例患者采用联合氨基糖苷类药物的治疗方案。此外,每天进行局部治疗,包括仔细清洁外耳道并局部应用抗菌药物。8例患者因药物治疗效果不佳而接受了感染软组织及死骨的手术清创。仅1例患者接受了高压氧治疗。治愈率估计为86%。仅1例患者死亡。
坏死性外耳道炎是一种严重感染。自对铜绿假单胞菌有效的抗生素问世以来,其预后已显著改善。必须立即开始治疗,且治疗必须延长。