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印度北方邦乌纳奥地区通过食用蔬菜和谷物摄入氟化物导致的特定部位毒理学风险。

Site specific toxicological risk from fluoride exposure through ingestion of vegetables and cereal crops in Unnao district, Uttar Pradesh, India.

机构信息

Central Soil Salinity Research Institute, Regional Research Station, Jail Road, Lucknow, Uttar Pradesh, India.

出版信息

Ecotoxicol Environ Saf. 2011 May;74(4):940-6. doi: 10.1016/j.ecoenv.2011.01.002. Epub 2011 Feb 16.

DOI:10.1016/j.ecoenv.2011.01.002
PMID:21329982
Abstract

A study was carried out to assess toxicological risk from the fluoride (F) exposure due to ingestion of vegetables and cereal crops such as rice and wheat grown in potentially fluoridated area (brick kiln and sodic areas), of different age groups in Unnao district, Uttar Pradesh, India. Fluoride contents in vegetables and cereal were found to be in the order brick kiln sites>sodic sites>normal sites. Among vegetables maximum F concentration was found in spinach and mint, whereas in cereal crops, wheat accumulated more F than rice. The exposure dose of F was determined using estimated daily intake (EDI) and bio-concentration factor (BCF) of F. The children of age group 3-14 years in the potentially fluoridated area were found to be at the risk of fluorosis. The mean BCF value of F was the highest in mint (36.6 mg/kg(dwt) plant/mg/kg(dwt) soil), followed by spinach (33.99 mg/kg(dwt) plant.mg/kg(dwt) soil).

摘要

一项研究旨在评估印度北方邦乌纳奥地区(砖窑和苏打地区)不同年龄段人群因摄入可能含氟地区(砖窑和苏打地区)种植的蔬菜和谷物(如大米和小麦)而导致的氟(F)暴露的毒理学风险。研究发现,蔬菜和谷物中的氟含量顺序为砖窑地区>苏打地区>正常地区。在蔬菜中,F 的最大浓度出现在菠菜和薄荷中,而在谷物作物中,小麦比大米积累了更多的 F。通过估计每日摄入量(EDI)和 F 的生物浓缩因子(BCF)来确定 F 的暴露剂量。研究发现,年龄在 3-14 岁之间的潜在氟化区儿童有氟中毒的风险。F 的平均 BCF 值在薄荷中最高(36.6 mg/kg(干重)植物/mg/kg(干重)土壤),其次是菠菜(33.99 mg/kg(干重)植物/mg/kg(干重)土壤)。

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