Department of PM&R, Indiana University School of Medicine, Indianapolis, Indiana 46254, USA.
J Neurotrauma. 2011 May;28(5):745-53. doi: 10.1089/neu.2010.1573. Epub 2011 Apr 12.
The precise measurement of patient outcomes depends upon clearly articulated constructs and refined clinical assessment instruments that work equally well for all subgroups within a population. This is a challenging task in those with acquired brain injury (ABI) because of the marked heterogeneity of the disorder and subsequent outcomes. Although essential, the iterative process of instrument refinement is often neglected. This present study was undertaken to examine validity, reliability, dimensionality and item estimate invariance of the Mayo-Portland Adaptability Inventory - 4 (MPAI-4), an outcome measure for persons with ABI. The sampled population included 603 persons with traumatic ABI participating in a home- and community-based rehabilitation program. Results indicated that the MPAI-4 is a valid, reliable measure of outcome following traumatic ABI, which measures a broad but unitary core construct of outcome after ABI. Further, the MPAI-4 is composed of items that are unbiased toward selected subgroups except where differences could be expected [e.g., more chronic traumatic brain injury (TBI) patients are better able to negotiate demands of transportation than more acute TBI patients]. We address the trade-offs between strict unidimensionality and clinical applicability in measuring outcome, and illustrate the advantages and disadvantages of applying single-parameter measurement models to broad constructs.
患者结局的精确测量取决于清晰表达的结构和经过改进的临床评估工具,这些工具在人群中的所有亚组中同样有效。在获得性脑损伤 (ABI) 患者中,这是一项具有挑战性的任务,因为该疾病及其随后的结果存在明显的异质性。尽管这是必不可少的,但仪器改进的迭代过程往往被忽视。本研究旨在检查 Mayo-Portland 适应能力量表 - 4(MPAI-4)的有效性、可靠性、维度和项目估计不变性,这是一种用于 ABI 患者的结局测量工具。抽样人群包括 603 名外伤性 ABI 患者,他们参加了家庭和社区康复计划。结果表明,MPAI-4 是外伤性 ABI 后结局的有效、可靠的测量工具,它测量了 ABI 后广泛但单一的核心结局结构。此外,MPAI-4 由针对特定亚组无偏见的项目组成,除非可以预期差异[例如,更多慢性创伤性脑损伤 (TBI) 患者比更急性 TBI 患者更能够应对交通需求]。我们在测量结局时讨论了严格的单维性和临床适用性之间的权衡,并说明了将单参数测量模型应用于广泛结构的优缺点。