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[西班牙输入性麻风病的当前挑战:7例病例研究]

[The current challenge of imported leprosy in Spain: a study of 7 cases].

作者信息

Contreras-Steyls M, López-Navarro N, Herrera-Acosta E, Castillo R, Ruiz del Portal G, Bosch R J, Herrera E

机构信息

Servicio de Dermatología, Hospital Clínico Universitario Virgen de la Victoria, Málaga, Spain.

出版信息

Actas Dermosifiliogr. 2011 Mar;102(2):106-13. doi: 10.1016/j.ad.2010.10.008. Epub 2011 Feb 22.

DOI:10.1016/j.ad.2010.10.008
PMID:21334586
Abstract

BACKGROUND

although the foci of leprosy once present in Spain are now under control and almost inactive, isolated cases are still occasionally diagnosed. Meanwhile, population migration has brought about an increase in the incidence of cases corresponding to individuals from countries where leprosy is endemic, leading to changes in the epidemiology of this disease.

OBJECTIVES

the aim of this paper was to describe the clinical, epidemiologic, dermatologic, microbiologic, and therapeutic characteristics of cases of leprosy in our department in the last 5 years.

MATERIAL AND METHODS

we report the cases of imported leprosy seen in our department between 2004 and 2009.

RESULTS

seven patients with leprosy (3 men and 4 women; age range, 26-80 years) were diagnosed; 2 were cases of tuberculoid leprosy, 2 borderline tuberculoid leprosy, and 3 indeterminate. All patients acquired the disease in South American or South African countries, but were residing in Spain at the time of diagnosis. One patient was a Spaniard, from Malaga, who had worked as a missionary in Venezuela for 25 years. The presence of the bacterium by either Ziehl-Neelsen stain or bacilloscopy could not be demonstrated in any of the patients.

CONCLUSIONS

we would like to draw attention to the changes we have observed in the characteristics of cases of leprosy seen in our department, the majority of which are imported. It is important to maintain a clinical suspicion of leprosy in cases of granulomatous dermatitis, particularly in patients from countries where the disease is endemic.

摘要

背景

尽管西班牙曾经存在的麻风病疫源地目前已得到控制且几乎不再活跃,但仍偶尔会诊断出个别病例。与此同时,人口迁移导致来自麻风病流行国家的个体所对应病例的发病率上升,从而使这种疾病的流行病学发生了变化。

目的

本文旨在描述过去5年我们科室麻风病病例的临床、流行病学、皮肤、微生物学及治疗特征。

材料与方法

我们报告了2004年至2009年在我们科室所见的输入性麻风病病例。

结果

诊断出7例麻风病患者(3名男性和4名女性;年龄范围为26 - 80岁);2例为结核样型麻风,2例为界线类偏结核样型麻风,3例为未定类。所有患者均在南美或南非国家感染该病,但诊断时居住在西班牙。1例患者是来自马拉加的西班牙人,他曾在委内瑞拉做了25年传教士。通过萋 - 尼氏染色或细菌镜检均未在任何患者中证实有细菌存在。

结论

我们想提请注意我们在科室所见麻风病病例特征方面观察到的变化,其中大多数为输入性病例。对于肉芽肿性皮炎病例,尤其是来自麻风病流行国家的患者,保持对麻风病的临床怀疑很重要。

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