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英格兰中部地区人群中黑色素瘤的十年审计。

Ten-year audit of melanoma in a central England population.

机构信息

Department of Plastic Surgery, University Hospitals of North Staffordshire NHS Trust, Stoke-on-Trent, UK.

出版信息

Acta Derm Venereol. 2011 Jun;91(4):440-3. doi: 10.2340/00015555-1069.

Abstract

The incidence of melanoma in the North Staffordshire region has more than doubled over the last 10 years, and nearly tripled in the "thin" melanoma group (≤ 1 mm). A retrospective audit was performed to investigate the overall management of melanoma, with a focus on thin melanomas. A total of 507 patients was identified between 1999 and 2009. The incidence of melanoma is increasing in the older age groups (> 50 years), although the thin melanomas were diagnosed at a significantly younger age than the cohort as a whole (p < 0.001). The anatomical distribution was similar in both groups. More females were affected by thin melanomas (65%) compared with all melanomas (55%). This audit provides a unique insight into the incidence and characteristics of melanoma in a Central England population. The incidence of melanoma is increasing, but more so in the thin group. Thick (> 4 mm) and intermediate (1.01-4 mm) melanomas are increasing at a slower rate.

摘要

过去 10 年来,北斯塔福德郡地区的黑色素瘤发病率增加了一倍以上,而“薄型”(≤ 1 毫米)黑色素瘤的发病率几乎增加了两倍。我们开展了一项回顾性审计,以调查黑色素瘤的整体管理情况,重点关注薄型黑色素瘤。1999 年至 2009 年间共发现 507 例患者。尽管薄型黑色素瘤的诊断年龄明显低于整个队列(p < 0.001),但黑色素瘤在年龄较大的人群(> 50 岁)中的发病率仍在增加。两组的解剖分布相似。与所有黑色素瘤(55%)相比,更多的女性受到薄型黑色素瘤(65%)的影响。该审计提供了对英格兰中部人群黑色素瘤发病率和特征的独特见解。黑色素瘤的发病率在增加,但在薄型组中增加得更多。厚型(> 4 毫米)和中厚型(1.01-4 毫米)黑色素瘤的增长速度较慢。

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